Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses.
説明 | (R)-Elagolix (NBI-56418) is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. |
ターゲット&IC50 | GnRHR: Ki : 3.7 nM, GnRHR:0.25 nM |
別名 | NBI-56418 |
分子量 | 631.59 |
分子式 | C32H30F5N3O5 |
CAS No. | 834153-87-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (158.33 mM)
You can also refer to dose conversion for different animals. 詳細
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(R)-Elagolix 834153-87-6 GPCR/G Protein GNRH Receptor Inhibitor GnRH Receptor NBI-56418 (R) Elagolix GNRHR Gonadotropin releasing hormone receptor Elagolix NBI 56418 NBI56418 inhibit (R)Elagolix inhibitor