Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 865,500 |
50 mg | 約10-14 週間 | ¥ 1,143,000 |
100 mg | 約10-14 週間 | ¥ 1,606,500 |
In vitro | (RS)-AMPA activates glutamate/quisqualate receptors to induce depolarizing effects without influencing NMDA receptors. It enhances the discharge rate of spontaneously active neurons or triggers a brief burst of action potentials in inactive cells. The depolarization effect of (RS)-AMPA is dose-dependent but shows significant variability across different neurons. At concentrations of 10^-3 to 10^-4 M, (RS)-AMPA causes depolarizations in cultured rat spinal and brainstem neurons. Lower concentrations (10^-5 M) result in minimal depolarizations (3-7 mV), while higher concentrations (10^-4 M) generate larger depolarizations, varying from 4 to 33 mV [1]. |
別名 | (±)-AMPA |
分子量 | 186.17 |
分子式 | C7H10N2O4 |
CAS No. | 77521-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(RS)-AMPA 77521-29-0 Membrane transporter/Ion channel Neuroscience iGluR glutamate neurotransmitter kainic Ionotropic glutamate receptors NMDA Inhibitor CNS (RS) AMPA (±)-AMPA AMPA L-glutamic inhibit interneurones Depolarizations motoneurones (RS)AMPA inhibitor