|
T6259 |
Dizocilpine
|
MK-801 |
NMDAR
,
iGluR
|
|
MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM. |
|
TP1253 |
Argireline
|
Acetyl hexapeptide-3 |
Others
|
|
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argirelin... |
|
T4297 |
Flibanserin
|
BIMT-17BS,Girosa,BIMT-17 |
Dopamine Receptor
,
5-HT Receptor
|
|
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n... |
|
T16800 |
(RS)-AMPA
|
(±)-AMPA |
iGluR
|
|
|
|
T3320 |
Dizocilpine Maleate
|
(+)-Mk-801 Hydrogen Maleate,MK 801,Dizocilpine hydrogen maleate,(+)-MK 801 maleate,(+)-MK 801 (Maleate) |
NMDAR
,
iGluR
|
|
Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of ne... |
|
T3269 |
Metadoxine
|
pyridoxine-pyrrolidone carboxylat,Metasin,Metadoxil |
5-HT Receptor
,
PKA
|
|
Metadoxine (Metadoxil) is a neurotransmitter stimulant. |
|
T12352L |
Oxidopamine hydrobromide
|
6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide |
Mitophagy
,
Dopamine Receptor
,
Autophagy
|
|
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist. |
|
T12352 |
Oxidopamine hydrochloride
|
6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride |
Mitophagy
,
Dopamine Receptor
,
Autophagy
|
|
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist. |
|
T26930 |
BW-1370U87
|
1370U 87,1370U-87,1370U87,BW 1370U87 |
|
|
BW-1370U87 is a monoamine oxidase A (MAO-A) inhibitor. BW-1370U87 elevates neurotransmitter amines in the brain over the same dose range at which it exhibits positive activities in animal models of depressive illness. BW... |
|
T2990 |
Phenibut
|
Phenybut,Fenigam,Fenibut,PhGABA,Aminophenylbutyric acid,β-Phenyl-γ-aminobutyric acid |
GABA Receptor
|
|
Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA). |
|
T0426 |
Piracetam
|
UCB-6215 |
GluR
,
iGluR
|
|
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders. |
|
T0290 |
Tizanidine hydrochloride
|
Tizanidine HCl,DS 103-282 |
Adrenergic Receptor
|
|
Tizanidine hydrochloride (Tizanidine HCl), an α2-adrenergic receptor agonist, inhibits neurotransmitter release from CNS noradrenergic neurons. |
|
TP2309 |
NEUROTENSIN TFA (39379-15-2 free base)
|
Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH TFA（55508-42-4 free base),NEUROTENSIN TFA |
Others
|
|
Neurotensin TFA (39379-15-2 free base) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a... |
|
T7401 |
(S)-3-AMino-2-Methylpropanoic acid-HCl
|
|
Others
|
|
(S)-3-AMino-2-Methylpropanoic acid-HCl is an amino acid derivative that can be an agonist of the excitatory neurotransmitter glutamate and affect the nervous system. |
|
T9857L |
Vasopressin acetate
|
Vasopressin acetate (11000-17-2 Free base) |
Endogenous Metabolite
|
|
Vasopressin acetate, a cyclic nonapeptide, is synthesized centrally in the hypothalamus. Vasopressin acetate acts as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors. |
|
T0719 |
Tetrabenazine
|
Xenazine,Ro 1-9569 |
Others
,
Dopamine Receptor
,
Monoamine Transporter
|
|
Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high... |
|
T0267 |
Zonisamide
|
AD 810,CI 912 |
Calcium Channel
,
Sodium Channel
,
Carbonic Anhydrase
|
|
Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures. It may inhibit a carbonic anhydrase although this is not one of the main mechanisms... |
|
T4174 |
NSC 191412
|
|
Others
|
|
NSC 191412 interacts with a variety of enzymes and receptors, including acetylcholinesterase and receptors for the neurotransmitter dopamine, and is an agonist or activator of these enzymes and receptors. |
|
T2663 |
GTS-21 dihydrochloride
|
GTS 21 dihydrochloride,DMXB-A,DMBX-anabaseine |
5-HT Receptor
,
AChR
|
|
GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh. |
|
T11393 |
GET73
|
Gamma hydroxybutyric acid analogue,GET 73 |
GluR
|
|
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. |
|
T1471 |
Duloxetine hydrochloride
|
Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i... |
|
TP1981L |
Neuropeptide S (Mouse) acetate
|
|
Neuropeptide Y Receptor
|
|
Neuropeptide S (Mouse) acetate is a bioactive peptide. Neuropeptide S (Mouse) acetate, as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behavio... |
|
T4440 |
Saclofen
|
|
GABA Receptor
|
|
Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function... |
|
T3534 |
Tetrabenazine Racemate
|
Nitoman,Ro 1-9569 Racemate,Rubigen,TETRABENAZINE |
Monoamine Transporter
|
|
Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). Tetrabenazine Racemate blocks neurotransmitter uptake into adrenergic storage vesicles and has been ... |
|
T9146 |
Ms48107
|
Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro- |
Others
|
|
MS48107 is a potent, selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68), demonstrating specificity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion ch... |
|
T7783 |
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE
|
|
Others
|
|
2-(4-TRIFLUOROMETHYL-PHENYL)-ETHYLAMINE is a monoamine neurotransmitter. It has been studied for its potential to modulate the activity of various neurotransmitters, including serotonin, dopamine, and norepinephrine. Its... |
|
T6604 |
Nepicastat hydrochloride
|
Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl |
Hydroxylase
|
|
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta... |
|
T20344 |
Acetylcholine bromide
|
|
Others
|
|
Acetylcholine bromide is the bromide salt of acetylcholine. It is an neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, a... |
|
T50046 |
2-(2-amino-3-methylbutanamido)-3-phenylpropanoic acid hydrochloride
|
|
Others
|
|
2-(2-amino-3-methylbutanamido)-3-phenylpropanoic acid hydrochloride is an amino acid compound that is a synthetic analog of glutamate, an important neurotransmitter in the central nervous system. It has been investigated... |
|
T50094 |
DL-Willardiine
|
2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid |
Others
|
|
DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate. It is an agonist of mGluR5, which regulates the activity of enzymes involved in... |
|
T9340 |
1-phenyl-3,4-dihydroisochinoline
|
3,4-Dihydro-1-phenylisoquinoline |
Others
|
|
1-phenyl-3,4-dihydroisochinoline (3,4-Dihydro-1-phenylisoquinoline) is a structural analog of the neurotransmitter dopamine that interacts with dopamine receptors in the central nervous system. It has been studied as a p... |
|
T16263 |
N6-Cyclopentyladenosine
|
UK-80882,CPA |
Adenosine Receptor
|
|
N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of 2.3 nM, 790 nM, and 43 nM for human A1, A2A, and A3 recepto... |
|
T9492 |
3-METHOXY-DL-TYROSINE
|
|
Others
|
|
3-METHOXY-DL-TYROSINE is a naturally occurring, non-essential amino acid found in the human body and many other organisms. It is a precursor to the neurotransmitter dopamine and is involved in the regulation of dopamine ... |
|
T50008 |
2,2-Dimethyl-5-(2,5-xylyloxy)valeramide
|
5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide |
Others
|
|
2,2-Dimethyl-5-(2,5-xylyloxy)valeramide (5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide) is a compound of the phenoxy family. It has been shown to have stimulatory effects on the nervous system, including increased neur... |
|
T37816 |
SB 243213
|
|
|
|
SB 243213 is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. SB 243213 shows greater than a 100-fold selectivity over a wide range o... |
|
T41194 |
FFN 102 mesylate
|
|
Others
|
|
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine... |
|
T3354 |
BIA 10-2474
|
BIA10-2474 |
FAAH
,
Autophagy
|
|
BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o... |
|
T9857 |
Vasopressin
|
antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) |
Endogenous Metabolite
|
|
Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pit... |
|
T21409 |
GABOB (beta-hydroxy-GABA)
|
β-hydroxy-GABA,beta-hydroxy-GABA,GABOB |
|
|
GABOB is an anticonvulsant used to treat epilepsy. GABOB is an endogenous active metabolite, it is analogue to the neurotransmitter γ-aminobutyric acid (GABA), therefore may function as a neurotransmitter. |
|
T25107 |
Arginylphenylalaninamide
|
Rfamide,Arg-phe-NH2 |
|
|
Arginylphenylalaninamide, an FMRamide fragment, may be utilized as a neurotransmitter or neuromodulator by optic lobe neurons of different types. |
|
T22781 |
FFN 511
|
|
Others
|
|
Fluorescent false neurotransmitter (FFN) |
|
T21340 |
Pergolide
|
|
|
|
Pergolide, an ergoline-based dopamine receptor agonist, is used for the treatment of Parkinson's disease, which is associated with low levels of the neurotransmitter dopamine in the brain. |
|
T20522 |
Acetylcholine perchlorate
|
AI351678,AI3-51678,AI3 51678 |
|
|
Acetylcholine perchlorate is the perchlorate salt of acetylcholine. Acetylcholine, an endogenous neurotransmitter at cholinergic synapses, could amplify the action potential of the sarcolemma following by inducing muscle... |
|
T15743 |
Levomepromazine
|
Methotrimeprazine |
Others
|
|
Methotrimeprazine is an orally available neuroleptic agent. It is commonly used to relieve nausea and vomiting in palliative care settings. Levomepromazine has antagonist actions at multiple neurotransmitter receptor sit... |
|
T26260 |
Tetrabenazine methanesulfonate
|
NSC169886,NSC 169886,NSC-169886 |
|
|
Tetrabenazine methanesulfonate is a medicine formerly utilized as an antipsychotic and therapy for various movement disorders. Tetrabenazine methanesulfonate blocks neurotransmitter uptake into adrenergic storage vesicle... |
|
T39962 |
Valiloxibic acid
|
XWL-008,Acidum valiloxibicum |
|
|
Valiloxibic acid is a prodrug of γ-Hydroxybutyric acid (GHB).GHB is a naturally occurring neurotransmitter and a psychoactive drug, it acts on the GHB receptor and is a weak agonist at the GABAB receptor. |
|
T69578 |
D-Ibotenic Acid
|
|
|
|
D-Ibotenic Acid is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. It ... |
|
T0128L |
Vigabatrin Hydrochloride
|
γ-Vinyl-GABA hydrochloride |
GABA Receptor
|
|
Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase. |
|
T39565 |
L-Glutamic acid-15N
|
|
|
|
L-Glutamic acid-15N is the 15N-labeled version of L-Glutamic acid, an excitatory neurotransmitter and an agonist at metabotropic, kainate, NMDA, and AMPA glutamate receptor subtypes. It directly activates the release of ... |
|
T35835 |
FFN-102 (trifluoroacetate salt)
|
|
|
|
FFN-102 (trifluoroacetate salt) is a synthetic biogenic neurotransmitter analog with pH-dependent fluorescence and electroactivity. |
