keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.
説明 | Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects. |
In vivo | Rapastinel acetate (3mg/kg; i.v.) facilitated long-term potentiation (LTP) 1day-2weeks but not 4weeks post-dosing. Biweekly dosing with Rapastinel acetate sustained this effect for at least 8weeks. A single dose of Rapastinel acetate increased the proportion of whole-cell NMDAR current contributed by NR2B-containing NMDARs in the hippocampus 1week post-dosing, which returned to baseline by 4weeks post-dosing[1]. |
別名 | Rapastinel acetate (117928-94-6 Free base) |
分子量 | 473.52 |
分子式 | C20H35N5O8 |
CAS No. | 491872-39-0 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (47.52 mM)
You can also refer to dose conversion for different animals. 詳細
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Rapastinel acetate 491872-39-0 Membrane transporter/Ion channel Neuroscience NMDAR iGluR Rapastinel acetate (117928-94-6 Free base) 117928-94-6 Rapastinel Acetate 117928-94-6 Free base Inhibitor inhibitor inhibit