Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,500 | |||
5 mg | 在庫あり | ¥ 26,000 | |||
10 mg | 在庫あり | ¥ 38,000 | |||
25 mg | 在庫あり | ¥ 63,500 | |||
50 mg | 在庫あり | ¥ 91,500 | |||
100 mg | 在庫あり | ¥ 136,000 |
説明 | (Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion. |
ターゲット&IC50 | VEGFR3:20 nmol/L, VEGFR3:45 nmol/L |
別名 | SAR131675 |
分子量 | 358.39 |
分子式 | C18H22N4O4 |
CAS No. | 1092539-44-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. 詳細
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(Rac)-SAR131675 1092539-44-0 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Vascular endothelial growth factor receptor potent (Rac)-SAR-131675 Inhibitor inhibit SAR-131675 (Rac) SAR131675 SAR131675 selective SAR 131675 racemate (Rac)SAR131675 inhibitor