10518
687
365
2
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T35862 | Cucurbit[8]uril | Others | |
Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de... | |||
T9223 | RO-0335 | Reverse Transcriptase | |
RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is... | |||
T9215 | ELOVL6-IN-2 | Others | |
ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor. | |||
T9194 | UMB298 | Epigenetic Reader Domain | |
UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM. | |||
T9214 | ELOVL6-IN-1 | Others | |
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner... | |||
T9202 | DDO-5936 | HSP | |
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor. | |||
T9164 | BMS-986242 | BMS986242 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer. | |||
T25492 | Hepln-13 | Hepln 13,Hepln13 | c-Met/HGFR |
Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis. | |||
T9541 | CTB | Cholera Toxin B subunit | Epigenetic Reader Domain |
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells. | |||
T10525 | SCD1 inhibitor-4 | Dehydrogenase , Stearoyl-CoA Desaturase (SCD) | |
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes. | |||
T15032 | CYM50308 | S1P Receptor , LPL Receptor | |
CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM). CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more sel... | |||
T6977 | SB-366791 | SB366791 | TRP/TRPV Channel |
SB-366791 is a new and selective cinnamide TRPV1 antagonist. | |||
T36670 | JNJ-67856633 | MALT | |
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases. | |||
T26324 | VU0071063 | VU 0071063,VU-0071063 | Potassium Channel |
VU0071063 is a Kir6.2/SUR1 activator. | |||
T3691 | (Rac)-SAR131675 | SAR131675 | VEGFR |
(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h... | |||
T9276 | SBC-115337 | Others , Serine/threonin kinase | |
SBC-115337 is a PCSK9 inhibitor. | |||
T4697 | ABBV-744 | ABBV744 | Epigenetic Reader Domain , HIV Protease |
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS. | |||
T6052 | GW 441756 | Apoptosis , Raf , Trk receptor , CDK | |
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM. | |||
T28804 | Slingshot inhibitor D3 | JHN76359 | Others |
Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot. | |||
T2024 | A-803467 | A 803467,A803467 | Sodium Channel |
A-803467 is a selective NaV1.8 channel blocker. | |||
T35317 | Zopolrestat | CP 73850,CP73850,CP-73850,Zopolrestatum | Reductase |
Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM). | |||
T22282 | Brr2-IN-3 | Brr2 Inhibitor 9,Brr2 Inhibitor C9 | Others |
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders). | |||
T9167 | PF-9363 | CTX-3648 | Histone Acetyltransferase |
PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer. | |||
T23524 | W-84 dibromide | HDMPPA | AChR |
W-84 dibromide (HDMPPA) is a M2-receptor selective modulator. | |||
T6476 | Dofetilide | UK 68789,UK-68798,Tikosyn | Potassium Channel |
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik... | |||
T5159 | Olodaterol hydrochloride | BI-1744 HCl,BI 1744 hydrochloride | Adrenergic Receptor |
Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adrenergic receptors... | |||
T9199 | GLPG2938 | 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea | S1P Receptor , LPL Receptor |
GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2. | |||
T6804 | Chetomin | Chaetomin,NSC289491,BRN0077366 | Apoptosis , HSP , HIF |
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations. | |||
T76505 | Bradykinin potentiator B | ||
Bradykinin Potentiator B (also known as Bradykinin Potentiating Peptide B), derived from the venom of Agkistrodon halys blomhoffi, serves as a potent ACE inhibitor. It effectively inhibits the activity of bradykinin inhi... | |||
T76507 | Bradykinin potentiator C | ||
Bradykinin Potentiator C, a potent inhibitor of angiotensin-converting enzyme (ACE) with an inhibitory concentration (IC 50) of 7.1 μM for rabbit lung ACE, is regarded as a prototype for functional peptides [1]. | |||
T25173 | Bradykinin potentiator-5 | BPP-5a\,BPP 5a\,BPP5a\ | |
Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall. | |||
T22566 | Aminopotentidine | Others | |
H2 antagonist | |||
T63003 | NMDA receptor potentiator-1 | ||
NMDA receptor potentiator-1 (Compound 1368) is a subunit-selective NMDA receptor enhancer with IC50 values of 4 μM and 5 μM for NR2C and NR2D expression, respectively. | |||
T28276 | OV-potentiator-28 | OV potentiator 28 | |
OV-potentiator-28 is a potentiator of cancer virotherapy. OV-potentiator-28 significantly enhances virus replication-associated luciferase expression, specifically in tumors. | |||
T10550 | Bisindolylmaleimide X hydrochloride | BIM-X hydrochloride,Ro31-8425 hydrochloride | CDK , PKC |
Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM). | |||
T27937 | LY2881835 | LY 2881835,LY-2881835 | |
LY2881835 is a potent and selective GPR40 agonist. | |||
T22832 | H-8 (hydrochloride) | Others | |
potent inhibitor of PKA and PKG | |||
T27102 | CV-6209 | ||
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor. | |||
T28643 | S1P1-IN-Ex26 | ||
S1P1-IN-Ex26 is a potent, selective antagonist of S1P1 receptor. | |||
T40146 | Sec61-IN-1 | Sec61-IN-1 | Others |
Sec61-IN-1 is a potent sec61 inhibitor. | |||
T15614 | JJKK 048 | Lipase | |
JJKK 048 is a potent and selective MAGL inhibitor. | |||
T10746 | CDK9-IN-8 | CDK | |
CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM). | |||
T4051 | LDC4297 | LDC044297 | CDK , HSV |
LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor. | |||
T24488 | MLS000545091 | MLS-000545091,MLS 000545091 | |
MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor. | |||
T27482 | GSK572A | Others | |
GSK572A is a novel and potent potent inhibitor of EchA6, which can be used to treat tuberculosis. | |||
T2069 | TH287 | TH287 hydrochloride | DNA/RNA Synthesis , MTH1 |
TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16. | |||
T19840 | GSK-F1 | PI4KA inhibitor-F1 | PI4K |
GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor. | |||
T5013 | Brequinar | Bipenquinate,NSC 368390,DUP785 | Virus Protease , Dehydrogenase , DNA/RNA Synthesis |
Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses. | |||
T11941 | Manitimus | FK778 | Others |
T29930 | AM-1235 | AM 1235,AM1235 | Cannabinoid Receptor |
AM-1235 is a potent and selective cannabinoid receptor CB1 agonist. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21351 | Maytansine | NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine | Microtubule Associated , Antibiotic |
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. | |||
TN6774 | Emodin 6-O-β-D-glucoside | Glucoemodin | Others |
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ... | |||
T81418 | Potentillanoside A | ||
Potentillanoside A is a natural hepatoprotective compound [1]. | |||
T22644 | C2 Ceramide | Ceramide | Others |
A potent modulator of cell proliferation and differentiation. | |||
TN1160 | 1,2,3,6-Tetragalloylglucose | 1,2,3,6-Tetra-O-galloyl-β-D-glucose,TeGG | LDL , UGT |
1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransfera... | |||
T2937 | 4'-Demethylepipodophyllotoxin | 4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin | Microtubule Associated |
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly. | |||
TN4171 | Grossamide | NO Synthase | |
Grossamide (GSE) Grossamide is a lignan amide derived from thioguanosine.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) inhibitor.6-Thioguanosine (GSE) is a selective and potent miR-210 (miRNA-210) i... | |||
T8281 | (R)-Sulforaphane | L-Sulforaphane | Nrf2 |
(R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway. | |||
T7972 | Gallic aldehyde | HSV | |
Gallic aldehyde shows potent antiviral activity against HSV-1. | |||
T8433 | HQNO | Mitochondrial Metabolism | |
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species. | |||
T7981 | 2-Fluoroadenosine | Others | |
2-Fluoroadenosine is a potent inhibitor of lymphocyte-mediated cytolysis. | |||
T2736 | Sodium Demethylcantharidate | Sodium norcantharidin | Others , Endogenous Metabolite |
Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity. | |||
TN1469 | Cassiaside B | Others , Antibacterial | |
Cassiaside B is a natural product with potent antibacterial activity. | |||
T8273 | 4,6-Dioxoheptanoic acid | Succinylacetone | Others , Endogenous Metabolite |
4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis. | |||
T2266 | SantacruzaMate A | CAY-10683 | HDAC |
SantacruzaMate A (CAY-10683) is a potent and selective HDAC inhibitor. | |||
TQ0172 | 2''-O-Rhamnosylicariside II | Others | |
2''-O-Rhamnosylicariside II might be beneficial for improving postmenopausal osteoporosis. It shows potent antioxidant activity, with IC50 values of 11.5 ug/mL and 90.5 uM. | |||
TN1325 | (2S)-6-Prenylnaringenin | 6-Prenylnaringenin,6-PN | GABA Receptor |
(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin. (2S)-6-Prenylnaringenin is the most potent compound in the forebrain and acts as a positive allosteric modulator ... | |||
TN1626 | Eugenin | Others | |
Eugenin is a chromone isolated from Peucedanum japonicum.Eugenin potent antiplatelet aggregation activity | |||
TN1455 | Bryodulcosigenin | Immunology/Inflammation related | |
Bryodulcosigenin has anti-inflammatory effect, it shows potent inhibitory effects on EBV-EA induction. | |||
T3364 | Veratramine | NSC17821,NSC23880 | Sodium Channel |
Veratramine (NSC-23880)(NSC-17821; NSC-23880) is a potent signal transduction inhibitor for treating tumors. | |||
T8035 | 3'-Methoxyflavonol | NMU2R | |
3'-Methoxyflavonol is a potent, selective agonist of neuromedin U 2 receptor (NMU2R). | |||
T3S1447 | Arteannuin B | SARS-CoV , Ferroptosis | |
1. Arteannuin B has potent antimalarial activity. | |||
T3718 | Santonin | α-santonin,alpha-Santonin,Semenen | Others , Parasite |
Santonin (alpha-Santonin) is a potent antiparasitic agent. | |||
TQ0170 | Desacetylcinobufagin | Deacetylcinobufagin | Others |
Desacetylcinobufagin (Deacetylcinobufagin) , a natural product, shows potent activities against Hela and A375 cells in vitro. | |||
TN7051 | 2,4-Dihydroxybenzaldehyde | 4-Formylresorcinol,beta-Resorcylaldehyde,4-Hydroxysalicylaldehyde | Endogenous Metabolite |
2,4-Dihydroxybenzaldehyde (4-Formylresorcinol) is a resorcinol derivative with potent antioxidant and antibacterial activity. 2,4-Dihydroxybenzaldehyde is an endogenous metabolite. | |||
T21820 | Resistomycin | Geliomycin,Heliomycin | Antibiotic |
Resistomycin (Geliomycin), a pentacyclic polyketide antibiotic, exhibits potent anticancer properties by triggering apoptosis. | |||
T3888 | Scopolin | Murrayin,Scopoloside | Sirtuin |
Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for... | |||
T3S1957 | 9-amino-CPT | Aminocamptothecin,9-amino-2(S)-camptothecin,9-Aminocamptothecin | Topoisomerase |
9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity. | |||
T4614 | Ellipticine hydrochloride | Ellipticine HCl,NSC 71795 (hydrochloride) | Topoisomerase |
Ellipticine hydrochloride (NSC-71795 (hydrochloride)) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. | |||
TL0015 | Pyromeconic acid | 3-hydroxy-4H-pyran-4-one | Anti-infection |
Pyromeconic acid (3-hydroxy-4H-pyran-4-one) and derivatives thereof are potent inhibitors of endonuclease | |||
T31866 | FR901464 | FR 901464,FR-901464,WB 2663B | Others |
FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring. | |||
T4183 | Lavendustin A | RG-14355,NSC 678027 | EGFR , Tyrosinase |
lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. | |||
T22857 | Illudin S | Apoptosis , DNA Alkylator/Crosslinker , Antifungal | |
Illudin S (ILS) is a fungal sesquiterpene secondary metabolite with potent genotoxic and cytotoxic properties. | |||
T14065 | 9-Ethyladenine | 6-Amino-9-ethylpurine | AChR |
9-Ethyladenine (6-Amino-9-ethylpurine) is a partially potent APRT (adenine phosphoribosyltransferase) inhibitor [1]. | |||
TQ0188 | Miquelianin | Quercetin 3-glucuronide,Quercetin 3-O-glucuronide | stilbene oxidase , Endogenous Metabolite |
Miquelianin (Quercetin 3-glucuronide) is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. | |||
TN4871 | Pyrolin | Anti-infection | |
Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola. | |||
T3750 | 4-Hydroxyacetophenone | 4-Acetylphenol,Piceol,p-Acetylphenol,4'-Hydroxyacetophenone | HBV , Xanthine Oxidase |
4-Hydroxyacetophenone (4-Acetylphenol) is a potent xanthine oxidase inhibitor. | |||
TN1829 | Kakkalide | Dehydrogenase | |
Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects. | |||
TN1643 | Ferulamide | 4-Hydroxy-3-methoxycinnamide | PAFR , AChR |
Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation. | |||
T12536 | Pregnenolone monosulfate | 3β-Hydroxy-5-pregnen-20-one monosulfate | NMDAR |
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a potent nootropic steroid that positively regulates NMDA recordings, and can be used in studies of neuroticism and depression. | |||
T3S2152 | 23-Hydroxybetulinic acid | Anemosapogenin | Others |
23-Hydroxybetulinic acid (Anemosapogenin) shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed. | |||
T5S2204 | Sibiricose A6 | Antioxidant | |
1. Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression. 2. Sibiricose A6 shows potent antioxidant activity. | |||
TQ0217 | Gomisin G | P450 , HIV Protease | |
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9. | |||
TN1899 | Lycoramine | AChE | |
Lycoramine is a natural product isolated from Lycoris radiate. Lycoramine is a potent acetylcholinesterase (AChE) inhibitor | |||
T4S1521 | 1,4-Dicaffeoylquinic acid | HIV Protease | |
1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration... | |||
T4704 | L-Anserine nitrate | L-Anserine nitrate salt | Others , Endogenous Metabolite |
L-Anserine nitrate (L-Anserine nitrate salt) is a dipeptide found in most animal tissues. In model systems it is a potent Antioxidant and scavener of hydroxyl radicals. The compound inhibits nonenzymatic protein glycatio... | |||
TN1975 | Neosmitilbin | Neoastilbin | Others |
Neosmitilbin (Neoastilbin) may have antioxidant and anti-inflammatory activities, it shows potent inhibition of lens aldose reductase. | |||
T9155 | Fumagillol | Others , Antibacterial | |
Fumagillol is a direct precursor of the potent angiogenesis inhibitors TNP-470 and fumagillin. | |||
T2959 | Ginsenoside Rh2 | 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2 | Apoptosis , EGFR , Caspase , Endogenous Metabolite |
Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug. | |||
T12095 | Monomethyl fumarate | GPR , Drug Metabolite | |
Monomethyl fumarate is a potent agonist of GPR109A . | |||
------------------------ More ------------------------ |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPK-00823 | VEGF165 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-04902 | Complement C5a Protein, Mouse, Recombinant | Mouse | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-05057 | Complement C5 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-00653 | Complement C5 Protein, Human, Recombinant (Complement C5a) | Human | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPJ-00779 | TNF alpha Protein, Rabbit, Recombinant | Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty... | |||
TMPY-01633 | SOST Protein, Rat, Recombinant (His) | Rat | HEK293 |
Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima... | |||
TMPY-00925 | SOST Protein, Human, Recombinant (His) | Human | HEK293 |
Sclerostin, the protein product of the SOST gene, is a potent inhibitor of bone formation. Sclerostin protein is widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and prima... | |||
TMPY-01458 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPJ-01464 | IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) | Human | Human Cells |
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m... | |||
TMPJ-00735 | PDGF-BB Protein, Human, Recombinant | Human | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPY-01369 | AGRP Protein, Human, Recombinant (His) | Human | HEK293 |
Agouti Related Protein (AGRP, or AGRT), is an endogenous antagonist of the melanocortin receptors MC3R and MC4R found in the hypothalamus and exhibits potent orexigenic activity. AGRP can act as a competitive antagonist ... | |||
TMPY-06988 | Osteopontin Protein, Human, Recombinant (aa 17-166, His) | Human | HEK293 |
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an... | |||
TMPY-01288 | Osteopontin Protein, Human, Recombinant (His) | Human | HEK293 |
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an... | |||
TMPJ-00562 | PDGF-BB Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P... | |||
TMPJ-00603 | TL1A Protein, Mouse, Recombinant | Mouse | E. coli |
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ... | |||
TMPJ-00864 | VEGF165 Protein, Human, Recombinant | Human | Human Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator... | |||
TMPJ-00059 | IL-7 Protein, Human, Recombinant (His) | Human | Human Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions... | |||
TMPY-01717 | VEGF164 Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-02432 | VEGF164 Protein, Rat, Recombinant | Rat | Baculovirus-Insect Cells |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-04911 | VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated | Human,Cynomolgus | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPY-03698 | VEGF121b Protein, Human, Recombinant | Human | HEK293 |
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-... | |||
TMPJ-01469 | NGF Protein, Human, Recombinant (E. colli) | Mouse | E.coli |
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family ... | |||
TMPY-00754 | IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) | Human | HEK293 |
Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang... | |||
TMPY-00472 | IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) | Human | E. coli |
Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang... | |||
TMPY-04726 | IL-8/CXCL8 Protein, Human, Recombinant (His) | Human | Yeast |
Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang... | |||
TMPY-05084 | Fc epsilon RI Protein, Human, Recombinant | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-03054 | Fc epsilon RI Protein, Human, Recombinant (His) | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPY-01864 | CNTF Protein, Human, Recombinant (His) | Human | E. coli |
Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that has functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its act... | |||
TMPY-00665 | Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) | Human | HEK293 |
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam... | |||
TMPY-00095 | IL-3 Protein, Human, Recombinant (His) | Human | HEK293 |
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cell... | |||
TMPY-00297 | IL-3 Protein, Human, Recombinant(aa 20-152) | Human | E. coli |
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cell... | |||
TMPY-01630 | Syndecan-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development... | |||
TMPJ-00103 | CD28 Protein, Human/Cynomolgus, Recombinant (His) | Human,Cynomolgus | Human Cells |
T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. It belongs to the immunoglobulin(Ig) superfamily. CD28 is one of th... | |||
TMPY-02115 | R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) | Human | HEK293 |
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel... | |||
TMPY-04104 | LIF Protein, Human, Recombinant | Human | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-04278 | LIF Protein, Mouse, Recombinant | Mouse | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-03532 | LIF Protein, Human, Recombinant (His) | Human | HEK293 |
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met... | |||
TMPY-04845 | IL-3 Protein, Mouse, Recombinant | Mouse | HEK293 |
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cell... | |||
TMPY-02792 | GDNF Protein, Human, Recombinant (HEK293) | Human | HEK293 |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact... | |||
TMPY-02731 | SPINK4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPY-00695 | I-309 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 d... | |||
TMPY-01371 | IL-17RA Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secret... | |||
TMPY-02450 | Cathepsin D Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly... | |||
TMPY-03762 | E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadher... | |||
TMPY-02019 | CD59 Protein, Human, Recombinant (His) | Human | HEK293 |
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran... | |||
TMPY-05435 | ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis... | |||
TMPY-00463 | ENPP2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen... | |||
TMPY-02778 | ENPP2 Protein, Human, Recombinant (His) | Human | HEK293 |
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen... | |||
TMPY-06983 | IFN gamma Protein, Human, Recombinant (E. coli) | Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
------------------------ More ------------------------ |
カタログ番号 | 製品名 | ||
---|---|---|---|
L7200 | Calcium Channel Compound Library | 140 compounds | |
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening; | |||
L4020 | NO PAINS Compound Library | 9384 compounds | |