Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound in Black Walnut Kernels. It shows anti-inflammatory activity.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 27,000 |
5 mg | 在庫あり | ¥ 67,000 |
10 mg | 在庫あり | ¥ 99,500 |
25 mg | 在庫あり | ¥ 164,500 |
50 mg | お問い合わせ | ¥ 226,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 135,000 |
説明 | 1,3,6-Tri-O-galloyl-beta-D-glucose (1,3,6-Tri-O-galloylglucose) is a phenolic compound in Black Walnut Kernels. It shows anti-inflammatory activity. |
In vitro | The compounds were isolated by silica gel column chromatography, Sephadex LH-20 column chromatography and ODS column chromatography.Their structures were elucidated by spectral analyses and physicochemical properties. The anti-inflammatory activities of selected isolated compounds were evaluated as inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cell lines by Griess reaction. Eight compounds were obtained from n-butanol fraction oi Mangifera indica L. seed kernel, whose structures were elucidated as 4-O-ethylgallic acid (1), gallic acid (2), citric acid(3), 1,2,3,4,6-penta-O-galloylglucose(4),1,3,6-Tri-O-galloylglucose(5), hyperoside(6), quercetin-3-O-rhamnopyranoside(7), and mangiferin(8). Compounds 1, 2 and 4-8 exhibited potent inhibitory effect on NO production in LPS-induced macrophages, especially compounds 6 and 8 showed the best inhibitory activity with IC50 values of 16.5 and 19.5 μmol·L-1, respectively. |
植物由来 |
別名 | 1,3,6-Tri-O-galloyl-β-D-glucose, 1,3,6-Tri-O-galloylglucose |
分子量 | 636.47 |
分子式 | C27H24O18 |
CAS No. | 18483-17-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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1,3,6-Tri-O-galloyl-beta-D-glucose 18483-17-5 Immunology/Inflammation Immunology/Inflammation related inhibit 1,3,6-Tri-O-galloyl-β-D-glucose Inhibitor 1,3,6-Tri-O-galloylglucose 1,3,6-Tri-O-galloyl-b-D-glucose 1,3,6TriOgalloylbetaDglucose 1,3,6 Tri O galloyl beta D glucose inhibitor