Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim protein kinases. This compound is valuable in cancer research, with a notable application in studying prostate cancer [1].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 16,500 | |||
2 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 35,500 | |||
10 mg | 在庫あり | ¥ 50,000 | |||
25 mg | 在庫あり | ¥ 105,500 | |||
50 mg | 在庫あり | ¥ 154,500 | |||
100 mg | 在庫あり | ¥ 220,000 | |||
500 mg | 在庫あり | ¥ 443,000 |
説明 | Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim protein kinases. This compound is valuable in cancer research, with a notable application in studying prostate cancer [1]. |
In vitro | Pim-1/2 kinase inhibitor 1 (compound D14) (varying concentrations; 48 h) exhibits cytotoxicity to PC3 cells, with an IC of 11 μM [1]. Cell Cytotoxicity Assay [1] Cell Line: PC3 cells Concentration: varying concentrations Incubation Time: 48 h Result: Inhibited PC3 cells with an IC of 11 μM. |
分子量 | 235.26 |
分子式 | C11H9NO3S |
CAS No. | 6320-51-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (212.53 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Pim-1/2 kinase inhibitor 1 6320-51-0 Chromatin/Epigenetic JAK/STAT signaling Pim 2,4 Thiazolidinedione, 5 p methoxybenzylidene 2,4Thiazolidinedione, 5pmethoxybenzylidene Inhibitor inhibitor inhibit