Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2,3-Dihydroxy-4-methoxyacetophenone (2',3'-Dihydroxy-4'-methoxyacetophenone) is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 10,000 | |||
100 mg | 在庫あり | ¥ 13,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | 2,3-Dihydroxy-4-methoxyacetophenone (2',3'-Dihydroxy-4'-methoxyacetophenone) is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease. |
In vivo | Oral administered of 2,3-dihydroxy-4-methoxyacetophenone (1, 10, 20, 40 and 50mg/kg) to amnesic mice induced by scopolamine.?In Morris water maze test, 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg) improved the impairment of spatial memory induced by scopolamine.?2,3-Dihydroxy-4-methoxyacetophenone protect HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50 value: 10.94μM).?Furthermore, 2,3-dihydroxy-4-methoxyacetophenone was found to inhibit [Ca(2+)] accumulation in HT22 cells and had antioxidantive activity.?2,3-dihydroxy-4-methoxyacetophenone exert neuroprotective and cognitive-enhancing activities through its antioxidant activity.?2,3-dihydroxy-4-methoxyacetophenone improves cognitive function and may be helpful for the treatment of Alzheimer's disease. |
植物由来 |
別名 | 2',3'-Dihydroxy-4'-methoxyacetophenone |
分子量 | 182.17 |
分子式 | C9H10O4 |
CAS No. | 708-53-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (123.51 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
2,3-Dihydroxy-4-methoxyacetophenone 708-53-2 Membrane transporter/Ion channel Metabolism Calcium Channel inhibit 2,3Dihydroxy4methoxyacetophenone Inhibitor 2,3 Dihydroxy 4 methoxyacetophenone 2',3'-Dihydroxy-4'-methoxyacetophenone inhibitor