Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifically inhibits analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase with IC50 of 2 μM. 3MB-PP1 can be used for the research of cell division and hypha formation of Candida albicans.
説明 | 3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifically inhibits analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase with IC50 of 2 μM. 3MB-PP1 can be used for the research of cell division and hypha formation of Candida albicans. |
分子量 | 295.38 |
分子式 | C17H21N5 |
CAS No. | 956025-83-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (186.2 mM)
You can also refer to dose conversion for different animals. 詳細
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3MB-PP1 956025-83-5 Cell Cycle/Checkpoint PLK DAPK Inhibitor Polo-like Kinase (PLK) Cdk8 Leu93-ZIPK Plk1 Ssn3 3MBPP1 inhibit CDK 3MB PP1 Death associated protein kinase cell division arise Cyclin dependent kinase Candida albicans inhibitor