keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 22,000 |
5 mg | お問い合わせ | ¥ 60,500 |
10 mg | お問い合わせ | ¥ 85,000 |
25 mg | お問い合わせ | ¥ 142,500 |
50 mg | お問い合わせ | ¥ 217,000 |
100 mg | お問い合わせ | ¥ 325,000 |
説明 | 740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K. |
In vitro |
740 Y-P is a synthetic biotinylated peptide. 740 Y-P stimulates mitogenesis at the lowest concentration tested (1 mg/mL). The peptide stimulates mitogenesis in both the presence and absence of serum (0.5%) and in the former instance, a maximal response observed at 50 mg/mL. 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell-permeable SH2 domain-binding peptide [1]. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose-dependent and does not require insulin[2]. |
別名 | PDGFR 740Y-P(TFA), 740 Y-P(TFA), 740YPDGFR(TFA) |
分子量 | 3384.73 |
分子式 | C143H223F3N43O41PS3 |
CAS No. | TQ0003L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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740 Y-P(TFA)(1236188-16-1 free base) TQ0003L PI3K/Akt/mTOR signaling PI3K PDGFR 740Y-P(TFA) 740 Y P(TFA)(1236188 16 1 free base) 740 Y-P(TFA) 740 YP(TFA)(1236188161 free base) 740YPDGFR(TFA) Inhibitor inhibitor inhibit