Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 9,000 |
2 mg | 在庫あり | ¥ 12,500 |
5 mg | 在庫あり | ¥ 20,500 |
10 mg | 在庫あり | ¥ 33,000 |
25 mg | 在庫あり | ¥ 68,500 |
50 mg | お問い合わせ | ¥ 112,500 |
100 mg | お問い合わせ | ¥ 164,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 25,000 |
説明 | XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold selectivity than the closely related PI3K kinases. |
ターゲット&IC50 | mTOR:9.9 nM |
キナーゼ試験 | Determination of Enzyme IC50 Values: IC50 values are determined using a 10 concentration point, non-radioactive, functional assay that employs a fluorescence-based, coupled-enzyme format, according to the manufacturer's protocol (Z'-LYTE@biochemical assay). Kinase selectivity is determined using both the Z'-LYTE@ and Adapta@ kinase assay format. |
分子量 | 455.5 |
分子式 | C23H22FN3O4S |
CAS No. | 1251156-08-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 22 mg/mL (48.3 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XL388 1251156-08-7 Metabolism PI3K/Akt/mTOR signaling P450 PI3K mTOR inhibit Mammalian target of Rapamycin XL-388 Inhibitor XL 388 inhibitor