Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TG 100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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2 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 20,500 | |||
25 mg | 在庫あり | ¥ 41,000 | |||
50 mg | 在庫あり | ¥ 77,500 | |||
100 mg | 在庫あり | ¥ 113,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,000 |
説明 | TG 100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively. |
ターゲット&IC50 | PI3Kγ:50 nM, PI3Kα:165 nM, PI3Kβ:215 nM, PI3Kδ:24 nM |
In vitro | TG 100713 also strongly inhibits EC proliferation. [1] |
キナーゼ試験 | Kinase Assays: PI3K reactions are constructed by using recombinant human kinases, 3 μM ATP, phosphatidylinositol substrate, and cofactors, and reaction progression measured by using a luminescent-based detection system to quantify ATP consumption. Protein kinase assays are performed by using commercial screening services. |
細胞研究 | Human umbilical vein EC plated in 96-well cluster plates (5,000 cells/well) are cultured in assay medium (containing 0.5% serum and 50 ng/ml VEGF) in the presence or absence of test compounds (10 μM), and cell numbers are quantified by XTT assay.(Only for Reference) |
別名 | TG100713 |
分子量 | 254.25 |
分子式 | C12H10N6O |
CAS No. | 925705-73-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.5 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TG 100713 925705-73-3 PI3K/Akt/mTOR signaling PI3K PI3Kβ Inhibitor PI3Kα PI3Kγ inhibit TG100713 isoform TG-100713 Phosphoinositide 3-kinase PI3Kδ inhibitor