Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 68,500 | |||
10 mg | 在庫あり | ¥ 119,000 | |||
25 mg | 在庫あり | ¥ 193,500 | |||
50 mg | 在庫あり | ¥ 266,500 | |||
100 mg | 在庫あり | ¥ 360,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 72,000 |
説明 | AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM). |
ターゲット&IC50 | MCT2:10 nM(ki), MCT1:(ki)2.3 nM |
In vitro | AR-C155858, at concentrations ranging from 10 nM to 100 nM, effectively inhibits the activity of MCT1/MCT2 C-terminal chimeras[1]. This compound also demonstrates time- and concentration-dependent inhibition of MCT1 when expressed in Xenopus oocytes[2]. Furthermore, AR-C155858 exhibits an inhibitory effect on MCT2, achieving 70% inhibition at 10 nM, with inhibition levels increasing gradually, indicative of a dissociation constant (Ki) value significantly lower than 10 nM. |
分子量 | 461.53 |
分子式 | C21H27N5O5S |
CAS No. | 496791-37-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40 mg/mL (86.67 mM)
You can also refer to dose conversion for different animals. 詳細
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AR-C155858 496791-37-8 Membrane transporter/Ion channel Monocarboxylate transporter inhibit Inhibitor AR-C-155858 AR-C 155858 Monocarboxylate Transporter ARC155858 AR C155858 inhibitor