Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 16,500 | |||
5 mg | 在庫あり | ¥ 37,500 | |||
10 mg | 在庫あり | ¥ 60,500 | |||
25 mg | 在庫あり | ¥ 123,500 | |||
50 mg | 在庫あり | ¥ 209,500 | |||
100 mg | 在庫あり | ¥ 342,000 | |||
500 mg | 在庫あり | ¥ 686,500 |
説明 | ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders. |
ターゲット&IC50 | MCH1:13 nM, 5-HT2B:9.66 nM, 5-HT1A:16.9 nM |
分子量 | 461.93 |
分子式 | C23H26ClF2N5O |
CAS No. | 510733-97-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 22.5 mg/mL (48.7 mM)
DMSO: 9.0 mg/mL (19.4 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ATC 0175 hydrochloride 510733-97-8 Endocrinology/Hormones GPCR/G Protein Neuroscience Melanin-concentrating Hormone Receptor (MCHR) GPR 5-HT Receptor ATC-0175 Hydrochloride ATC 0175 Hydrochloride ATC0175 Hydrochloride Inhibitor inhibitor inhibit