keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 30,000 | |||
5 mg | 在庫あり | ¥ 103,500 | |||
10 mg | 在庫あり | ¥ 152,500 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
100 mg | 在庫あり | ¥ 431,500 |
説明 | ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization. |
In vitro | ATI-2341 induced CXCR4- and G protein-dependent signaling, receptor internalization, and chemotaxis in CXCR4-expressing cells[1]. |
In vivo | ATI-2341 induced dose-dependent peritoneal recruitment of PMNs when administered i.p. to mice. When administered systemically by i.v. bolus, ATI-2341 acted as a functional antagonist and dose-dependently mediated release of PMNs from the bone marrow of both mice and cynomolgus monkeys[1]. |
分子量 | 2316.87 |
分子式 | C106H182N26O27S2 |
CAS No. | T6764L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. 詳細
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ATI-2341 acetate(1337878-62-2 free base) T6764L Autophagy GPCR/G Protein Immunology/Inflammation CXCR ATI2341 acetate(1337878622 free base) ATI 2341 acetate(1337878 62 2 free base) Inhibitor inhibitor inhibit