Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.
説明 | AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. |
ターゲット&IC50 | CDK2 (WT):50 nM(Kd), CDK2 (C118L):18.6 nM(Kd), CDK2 (C118L/A144C):9.7 nM(Kd), CDK2 (A144C):15.4 nM(Kd) |
In vitro | K03861 inhibits CDK2 activity by competing with binding of activating cyclins. [1] |
別名 | K03861 |
分子量 | 501.5 |
分子式 | C24H26F3N7O2 |
CAS No. | 853299-07-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 12 mg/mL (23.9 mM)
DMSO: 93 mg/mL (185.4 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AUZ 454 853299-07-7 Cell Cycle/Checkpoint CDK ACHN AUZ454 Caki-1 cells K 03861 Cyclin dependent kinase Inhibitor inhibit CDK2 K03861 K-03861 AUZ-454 inhibitor