Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 14,500 | |||
5 mg | 在庫あり | ¥ 34,000 | |||
10 mg | 在庫あり | ¥ 55,000 | |||
25 mg | 在庫あり | ¥ 99,500 | |||
50 mg | 在庫あり | ¥ 146,500 | |||
100 mg | 在庫あり | ¥ 205,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 38,500 |
説明 | AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel. |
In vivo | Following a single dose (AZD3229, 20 mg/kg), high free cover over the target is achieved and is associated with complete suppression of pKIT and downstream markers out to 8 hours. As the compound is cleared and cover declines, these signals recover although recovery is not complete even at 24 hours. |
分子量 | 479.51 |
分子式 | C24H26FN7O3 |
CAS No. | 2248003-60-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: 95 mg/mL (198.12 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AZD3229 2248003-60-1 Tyrosine Kinase/Adaptors c-Kit Inhibitor AZD-3229 CD117 AZD 3229 SCFR inhibit inhibitor