Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.
説明 | AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma. |
In vitro | The affinity of AZD5423 to the glucocorticoid receptor is high with an IC50 of 0.9 nM in a radioligand human glucocorticoid receptor assay. And it selectivity towards other steroid hormone receptors is >900-fold[1]. |
分子量 | 487.45 |
分子式 | C25H21F4N3O3 |
CAS No. | 1034148-04-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (205.15 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AZD5423 1034148-04-3 Endocrinology/Hormones Glucocorticoid Receptor AZD 5423 AZD-5423 Inhibitor inhibit inhibitor