Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 8,500 | |||
10 mg | 在庫あり | ¥ 14,000 | |||
25 mg | 在庫あり | ¥ 27,000 | |||
50 mg | 在庫あり | ¥ 44,000 | |||
100 mg | 在庫あり | ¥ 68,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod. |
In vivo | A single oral administration of afoxolaner at a dose near the minimum effective (2.5mg/kg) eradicated existing I. scapularis tick infestations and managed weekly re-infestations effectively. Efficiencies ranged from 98% to 100% up to Day 23 and remained at 94% on Day 30 [1]. |
分子量 | 625.87 |
分子式 | C26H17ClF9N3O3 |
CAS No. | 1093861-60-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: ≥ 250 mg/mL (399.44 mM)
You can also refer to dose conversion for different animals. 詳細
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Afoxolaner 1093861-60-9 Membrane transporter/Ion channel Microbiology/Virology Neuroscience Chloride channel GABA Receptor Parasite acaricide isoxazoline Inhibitor arthropod Cl? Channels scapularis dog γ-Aminobutyric acid Receptor Chloride Channel insecticide inhibit insect Gamma-aminobutyric acid Receptor Ixodes inhibitor