Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
説明 | Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. |
別名 | Somalgen |
分子量 | 414.33 |
分子式 | C21H13F3N2O4 |
CAS No. | 66898-62-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL
You can also refer to dose conversion for different animals. 詳細
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Talniflumate 66898-62-2 Immunology/Inflammation Membrane transporter/Ion channel Metabolism Neuroscience Chloride channel Anion Exchanger N-Acetylglucosaminyltransferase COX inhibit asthma cystic fibrosis Inhibitor Somalgen pulmonary obstructive Chloride Channel anti-inflammatory BA 7602-06 COPD Cl? Channels chronic ulcerogenic Intestinal disease analgesic inhibitor