Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 9,500 | |||
25 mg | 在庫あり | ¥ 15,500 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 30,500 | |||
200 mg | 在庫あり | ¥ 45,500 | |||
500 mg | お問い合わせ | ¥ 77,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,500 |
説明 | Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), which is then cleaved to aripiprazole, which is non-toxic. |
In vivo | Intravenous administration of 1.87?mg/ml Aripiprazole lauroxil bioconversion in vivo involves the formation of an intermediate,?N-hydroxymethyl aripiprazole. The?in vitro?data indicates a high bioconversion of aripiprazole lauroxil, thus, the concentration of?N-hydroxymethyl aripiprazole observed in the animals dosed with aripiprazole lauroxil is surprisingly high[1]. |
分子量 | 660.71 |
分子式 | C36H51Cl2N3O4 |
CAS No. | 1259305-29-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/mL (12.11 mM)
You can also refer to dose conversion for different animals. 詳細
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Aripiprazole Lauroxil 1259305-29-7 GPCR/G Protein Neuroscience 5-HT Receptor Dopamine Receptor schizophrenia Aristada inhibit Inhibitor inhibitor