Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3 receptors.BAY 60-6583 is cardioprotective in a model of myocardial ischemia.The Ki values for BAY 60-6583 binding to mouse, rabbit, and dog A2BAR were 750 nM, 340 nM, and 330 nM, respectively. The Ki values of BAY 60-6583 binding to A2BAR in mice, rabbits and dogs were 750 nM, 340 nM and 330 nM respectively.
説明 | BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3 receptors.BAY 60-6583 is cardioprotective in a model of myocardial ischemia.The Ki values for BAY 60-6583 binding to mouse, rabbit, and dog A2BAR were 750 nM, 340 nM, and 330 nM, respectively. The Ki values of BAY 60-6583 binding to A2BAR in mice, rabbits and dogs were 750 nM, 340 nM and 330 nM respectively. |
ターゲット&IC50 | A2BAR (mouse):750 nM, A2BAR (rabbit):340 nM, A2B:3 nM(EC50), A2BAR (dog):330 nM |
分子量 | 379.44 |
分子式 | C19H17N5O2S |
CAS No. | 910487-58-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (237.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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BAY 60-6583 910487-58-0 GPCR/G Protein Neuroscience Others Adenosine Receptor BAY 606583 BAY 60 6583 Inhibitor inhibitor inhibit