Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 85,500 | |||
10 mg | 在庫あり | ¥ 128,000 | |||
25 mg | 在庫あり | ¥ 206,000 | |||
50 mg | 在庫あり | ¥ 280,000 | |||
100 mg | 在庫あり | ¥ 379,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 91,500 |
説明 | BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM. It induces polymerization of BCL6 and facilitates its degradation in a manner dependent on the E3 ligase SIAH1, demonstrating notable antitumor activity[1][2]. |
ターゲット&IC50 | BCL6 BTB:≤ 3 nM |
In vitro | BI-3802 shows an IC50 of 43 nM for the cellular BCL6[1]. BI-3802 increases the interaction between BCL6 and SIAH1 (EC50 = 64 nM)[2]. |
分子量 | 484.98 |
分子式 | C24H29ClN6O3 |
CAS No. | 2166387-65-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mg/mL (10.31 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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BI-3802 2166387-65-9 Apoptosis BCL Inhibitor Bcl-2 Family BI 3802 inhibit BI3802 inhibitor