Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.
説明 | BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM. |
ターゲット&IC50 | CCR2:5.1 nM |
In vitro | BMS CCR2 22 inhibits the internalization of hMCP1_AF647 (IC50 = 2 nM)[2]. HAoECs with BMS CCR2 22 before MCP-1 increases the cell surface levels of VCAM-1 from 72.8 to 160% and PECAM1 from 97.2 and 127%[3]. |
分子量 | 593.66 |
分子式 | C28H34F3N5O4S |
CAS No. | 445479-97-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225.0 mg/mL (379.0 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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BMS CCR2 22 445479-97-0 Immunology/Inflammation Microbiology/Virology CCR BMS CCR-2 22 Inhibitor inhibitor inhibit