Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 60,500 | |||
10 mg | 在庫あり | ¥ 85,500 | |||
25 mg | 在庫あり | ¥ 144,500 | |||
50 mg | 在庫あり | ¥ 206,000 | |||
100 mg | 在庫あり | ¥ 280,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 66,000 |
説明 | BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator. |
In vitro | BMS-191095 elicits a dose-dependent vasodilation in endothelium-denuded cerebral arteries with 8.1 ± 2.3%, 31.6 ± 2.1%, and 39.5 ± 3.2% relaxation in response to 10, 50, and 100 μM, respectively. BMS-191095 induces mitochondrial-depolarization and vasodilation. |
In vivo | In normal rats, BMS-191095-induced vasodilation was mediated by mitochondrial depolarization and calcium sparks generation in VSM and was reduced by inhibition of BKCa channels. |
分子量 | 408.88 |
分子式 | C22H21ClN4O2 |
CAS No. | 166095-21-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (220.11 mM)
You can also refer to dose conversion for different animals. 詳細
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BMS-191095 166095-21-2 Membrane transporter/Ion channel Potassium Channel Inhibitor BMS191095 KcsA BMS 191095 inhibit inhibitor