Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 11,000 |
2 mg | お問い合わせ | ¥ 13,000 |
5 mg | お問い合わせ | ¥ 23,500 |
10 mg | お問い合わせ | ¥ 37,500 |
25 mg | お問い合わせ | ¥ 74,500 |
50 mg | お問い合わせ | ¥ 132,500 |
100 mg | お問い合わせ | ¥ 189,500 |
1 mL * 10 mM (in DMSO) | お問い合わせ | ¥ 23,500 |
説明 | BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction. |
ターゲット&IC50 | PD-1/PD-L1:18 nM |
別名 | PD-1/PD-L1 inhibitor 2 hydrochloride |
分子量 | 455.97 |
分子式 | C25H30ClN3O3 |
CAS No. | 2089334-95-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL(71.51 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BMS202 hydrochloride (1675203-84-5(free base)) 2089334-95-0 Apoptosis Cell Cycle/Checkpoint Immunology/Inflammation PD-1/PD-L1 PD-1/PD-L1 inhibitor 2 hydrochloride BMS-202 hydrochloride (1675203-84-5(free base)) BMS202 hydrochloride (1675203 84 5(free base)) PD-1/PD-L1 inhibitor 2 Hydrochloride BMS202 hydrochloride (1675203845(free base)) Inhibitor inhibitor inhibit