Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 13,500 | |||
2 mg | 在庫あり | ¥ 20,000 | |||
5 mg | 在庫あり | ¥ 33,000 | |||
10 mg | 在庫あり | ¥ 52,000 | |||
25 mg | 在庫あり | ¥ 105,500 | |||
50 mg | 在庫あり | ¥ 150,500 | |||
100 mg | 在庫あり | ¥ 211,000 |
説明 | BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM). |
ターゲット&IC50 | PTEN:14 nM(Cell-free assay) |
In vitro | 1 μM BpV(Hopic) is capable of enhancing the migration of C2C12 myoblasts by approximately 40 % in the presence of myotube conditioned media, without significantly affecting their capacity to differentiate and fuse into multinucleated myotubes.?Improved migration of myoblasts treated with 1 μM BpV(Hopic) was associated with activation of PI3K/AKT and MAPK/ERK pathways, while their inhibition with either LY294002 or UO126, respectively, resulted in a reduction of C2C12 migration back to control levels[1] |
別名 | bpV (HOpic) |
分子量 | 347.24 |
分子式 | C6H4K2NO8V |
CAS No. | 722494-26-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 10 mM
DMSO: Insoluble
You can also refer to dose conversion for different animals. 詳細
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BpV(HOpic) 722494-26-0 PI3K/Akt/mTOR signaling PTEN MAPK/ERK Phosphatase and tensin homolog Inhibitor HOpic MMAC1 bpV (HOpic) inhibit PI3K/AKT bpV signalling inhibitor