Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCR2 antagonist 5 (JNJ-41443532) is a selective and orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM).JNJ-41443532 binds mCCR2 with a Ki of 9.6 µM, which can be used to study inflammatory diseases and diabetes. diseases and diabetes.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 25,500 | |||
5 mg | 在庫あり | ¥ 62,000 | |||
10 mg | 在庫あり | ¥ 92,000 | |||
25 mg | 在庫あり | ¥ 153,500 | |||
50 mg | 在庫あり | ¥ 218,000 | |||
100 mg | 在庫あり | ¥ 296,000 | |||
500 mg | 在庫あり | ¥ 592,500 |
説明 | CCR2 antagonist 5 (JNJ-41443532) is a selective and orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM).JNJ-41443532 binds mCCR2 with a Ki of 9.6 µM, which can be used to study inflammatory diseases and diabetes. diseases and diabetes. |
ターゲット&IC50 | CCR2 (mouse):9.6 μM (Ki), CCR2 (human):37 nM (IC50) |
別名 | JNJ-41443532, JNJ-41443532 Free Base, JNJ 41443532, JNJ41443532 |
分子量 | 482.52 |
分子式 | C22H25F3N4O3S |
CAS No. | 1228650-83-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (103.62 mM)
You can also refer to dose conversion for different animals. 詳細
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CCR2 antagonist 5 1228650-83-6 Immunology/Inflammation Microbiology/Virology CCR JNJ-41443532 JNJ-41443532 Free Base JNJ 41443532 JNJ41443532 Inhibitor inhibitor inhibit