store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 7,000 | |||
10 mg | 在庫あり | ¥ 12,000 | |||
25 mg | 在庫あり | ¥ 19,500 | |||
50 mg | 在庫あり | ¥ 28,500 | |||
100 mg | 在庫あり | ¥ 42,000 | |||
500 mg | 在庫あり | ¥ 105,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,500 |
説明 | CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. |
In vitro | CORM-3 protects against hypoxia-reoxygenation and oxidative stress by promoting CO release in cardiac cells. [1] CORM-3 attenuates the inflammatory response induced by LPS in RAW264.7 murine macrophages. [2] CORM-3 also uncouples mitochondrial respiration via interaction with the phosphate carrier. [4] |
In vivo | CORM-3 (40 mg/kg i.p.) prolongs the survival of murine cardiac grafts and attenuates organ rejection in CBA mice transplanted with BALB/c hearts. [1] CORM-3 (20 mg/kg i.p.) decreases cellular infiltration, joint inflammation and destruction in a collagen-induced arthritis mouse model. [3] |
別名 | CORM3 |
分子量 | 294.61 |
分子式 | C5H4ClNO5Ru |
CAS No. | 475473-26-8 |
store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (169.72 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CORM-3 475473-26-8 Immunology/Inflammation NF-Κb Others NOD-like Receptor (NLR) NF-κB inhibit Inhibitor CORM 3 Nuclear factor-kappaB Nuclear factor-κB CORM3 inhibitor