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103

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天然化合物

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カタログ番号	製品名	別名	ターゲット
T63775	Anti-MRSA agent 1
	Anti-MRSA agent 1 is an MRSA inhibitor with an MIC value of 0.5 μg/mL and is effective in alleviating the effects of MRSA resistance.
T60546	Anti-MRSA agent 6
	Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].
T62383	Anti-MRSA agent 2
	Anti-MRSA agent 2 (compound 14) is a good inhibitor of methicillin-resistant Staphylococcus aureus (MRSA) (MIC: 0.098 μg/ml) with relatively low toxicity to normal cells. anti-MRSA agent 2 is a strong disruptor of bacter...
T74527	Anti-MRSA agent 4
	Anti-MRSA agent 4 (compound 7a), a selective and potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA) growth, demonstrates a minimum inhibitory concentration (MIC) of ≤ 0.26 µM. It exhibit...
T74810	Anti-MRSA agent 7
	Anti-MRSA agent 7 (Compound 12) serves as a potent antibacterial compound effectively inhibiting both S. aureus and E. coli DNA gyrases, as well as topo IV enzymes from the same organisms, with IC50 values of 0.185 μM, 0...
T62577	Anti-MRSA agent 5
	Anti-MRSA agent is a potent antagonist of MRSA (MIC50: 0.38 μg/mL) with low hERG activity (IC50: 40 μM). anti-MRSA agent also has low toxicity to mammalian cells and little potential to acquire bacterial resistance.
T63632	Anti-MRSA agent 3
	Anti-MRSA agent 3 inhibits methicillin-resistant Staphylococcus aureus (MRSA) activity significantly (MIC: 0.098 μg/ml) with low toxicity to normal cells. anti-MRSA agent 3 has a high binding affinity for bacterial genom...
T79778	Anti-MRSA agent 8
	Anti-MRSA Agent 8 (Compound 7g), a derivative of DAPG, exhibits potent antibacterial properties by interacting with bacterial cell membranes and is useful for studying methicillin-resistant Staphylococcus aureus (MRSA) [...
T7897	PK150		Others , Antibacterial
	PK150 shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations.		Others , Antibacterial
T8507	MAC-545496		Antibacterial
	MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.		Antibacterial
T22269	Benzyldodecyldimethylammonium Chloride Dihydrate		Antibacterial
	Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...		Antibacterial
T40475	Ceftobiprole medocaril	BAL5788	Antibacterial
	Ceftobiprole medocaril (BAL5788) is the parenteral prodrug of Ceftobiprole. Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA).		Antibacterial
TQ0077	Ceftobiprole	Ro 63-9141,BAL 9141	Antibacterial
	Ceftobiprole (Ro 63-9141) is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL).		Antibacterial
T7387	Ceftaroline fosamil	TAK-599,PPI0903	Antibacterial , Antibiotic
	Ceftaroline fosamil (TAK-599) is a cephalosporin, with activity against Gram-positive pathogens.		Antibacterial , Antibiotic
T21358	Dalbavancin	BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl	Antibacterial , Antibiotic
	Dalbavancin (BI-397), a novel second-generation lipoglycopeptide antibiotic, possesses in vitro activity against a variety of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and methi...		Antibacterial , Antibiotic
T4208	Targocil		Antibacterial
	Targocil is used as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) (MIC90s: 2 μg/ m...		Antibacterial
T61037	Glycosyltransferase-IN-1		Others
	Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.		Others
T2549	Robenidine hydrochloride	Rasexinium,Dexium,Robenidine Hydrochoride,Toraxine,Nugatex	Antibacterial , Antibiotic , Parasite
	Robenidine hydrochloride (Robenidine Hydrochoride) is an anticoccidial agent mainly used in poultry.		Antibacterial , Antibiotic , Parasite
T3114	Povidone iodine	Betadine,Povidone-iodine,Isodine,PVP iodine,iodopovidone,PVP-I	Antibacterial , Antibiotic
	Povidone iodine (Povidone-iodine) exhibits superior antibacterial properties, effectively targeting both MRSA and MSSA strains with minimum inhibitory concentrations (MICs) of 31.25 mg/L and 7.82 mg/L, respectively.		Antibacterial , Antibiotic
T36033	DETA NONOate	NOC-18,Diethylamine NONOate	NO Synthase
	DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infect...		NO Synthase
T67826	Alalevonadifloxacin		DNA gyrase , Topoisomerase , Antibacterial
	Alalevonadifloxacin is a DNA gyrase and DNA topoisomerase inhibitor and a novel antibacterial compound of the quinolone class targeting MRSa. Alalevonadifloxacin is potentially useful in the treatment of bacterial Gram-p...		DNA gyrase , Topoisomerase , Antibacterial
T64316	VP-4604	1-((4-Nitrophenyl)sulfonyl)piperidine
	VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 μg/mL. VP-4604 inhibited the growth of ...
T0391	Linezolid	PNU-100766	MAO , Antibacterial , Antibiotic
	Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRS...		MAO , Antibacterial , Antibiotic
T4165	Delpazolid	LCB01-0371	Antibacterial , Antibiotic
	Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomyc...		Antibacterial , Antibiotic
T74776	Antibacterial agent 139
	Antibacterial agent 139 exhibits antibacterial activity specifically targeting Gram-positive bacteria, including resistant strains such as MRSA (anti-MRSA), VISA (anti-VISA), and LRSE (anti-LRSE). It operates by depolari...
T80390	HG4
	HG4 is an antimicrobial peptide with rapid anti-biofilm and anti-inflammatory properties. It exhibits potent activity against Gram-positive pathogens, notably MRSA strains, with a minimum inhibitory concentration (MIC) r...
T39816	Ceftaroline fosamil inner salt	TAK-599 free acid,PPI0903freeacid
	Ceftaroline fosamil (TAK-599) inner salt, a cephalosporin derivative, is an N-phosphono prodrug of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil inner salt can be used for the resea...
T63224	Antibacterial agent 104
	Antibacterial agent 104 is an effective antibacterial agent with significant antibacterial effects in vitro and good anti-MRSA effects in vivo.
T31064	CP-5484	CP 5484,UNII-A53TMV6VUN,CP5484
	Cp-5484 is a new kind of Quaternary carbapenem with strong anti MRSA activity and low acute toxicity.
T80387	HG2
	HG2 is an antimicrobial peptide with rapid action, exhibiting anti-biofilm and anti-inflammatory properties. It is particularly efficacious against Gram-positive pathogens, including MRSA strains (MIC: 16-32 μg/mL), and ...
T74269	Antibacterial agent 83
	Antibacterial agent 83 (compound 17h) exhibits strong antibacterial efficacy against diverse strains of vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA), significant...
T30767	CB-181963	CB 181963,CB181963,UNII-6784994L0W,CAB 175
	CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.
T82761	CDFI
	CDFI, a lipid II flippase MurJ inhibitor, enhances the efficacy of β-lactams in combating MRSA [1] [2].
T73127	C16-K-cBB1
	C16-K-cBB1 is a potent, selective antimicrobial agent effective against Methicillin-resistant Staphylococcus aureus (MRSA), demonstrated by its minimal inhibitory concentration (MIC) of 1 µg/mL. This compound exhibits ex...
T61121	NusB-IN-1
	NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1].
T40301	Antibacterial agent 28
	Antibacterial agent 28, with a minimum inhibitory concentration (MIC) range of 0.5-2 μg/mL, exhibits promising potential as an antibacterial candidate targeting MRSA infections.
T80275	Lynronne-2
	Lynronne-2, an antimicrobial peptide, exhibits activity against Gram-positive bacteria, including methicillin-resistant MRSA strains (MIC: 32-256 μg/mL), and demonstrates effectiveness in combating P. aeruginosa infectio...
T74803	Levonadifloxacin
	Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771), a broad-spectrum anti-staphylococcal agent, exhibits antibacterial activity against both Methicillin-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S....
T35064	Viquidacin	NXL101,NXL-101,NXL 101
	Viquidacin ( NXL-101) is an oral/intravenous antibiotic that targets Gram-positive bacteria such as MRSA. In 2008, Novexel announced it had discontinued the development of Viquidacin (NXL 101).
T80274	Lynronne-1
	Lynronne-1, an antimicrobial peptide, exhibits activity against Gram-positive bacteria, including multi-drug resistant (MDR) strains, with a minimal inhibitory concentration (MIC) of 8-32 μg/mL for methicillin-resistant ...
T83098	Antibacterial agent 163
	Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, potently inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1].
T80414	ASP-1
	ASP-1 is a potent antistaphylococcal peptide, exhibiting minimum inhibitory concentrations (MICs) ranging from 2 μg/mL to 64 μg/mL against both S. aureus and methicillin-resistant S. aureus (MRSA) [1].
T74502	Antibacterial agent 108
	Compound 1h (Antibacterial agent 108) is a potent antibacterial agent, demonstrating a minimum inhibitory concentration (MIC) of 3 μM against both MRSA and antibiotic-resistant strains [1].
T83097	Antibacterial agent 165
	Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, effectively inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1], demonstrating its potent antibacterial properties.
T64069	Antibacterial agent 87
	Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).
T39230	Contezolid acefosamil	MRX-4,Contezolid acefosamil
	Contezolid acefosamil (MRX-4), an orally active prodrug, is metabolized into Contezolid (MRX-I), an oxazolidinone derivative with potent in vitro efficacy against multidrug-resistant Gram-positive bacteria, including MRS...
T63370	FtsZ-IN-2
	FtsZ-IN-2 is an inhibitor of the bacterial cytokinin FtsZ and has an inhibitory effect on GTPase activity. ftsZ-IN-2 exhibited anti-staphylococcal effects with MIC values of 2 μg/ml for both MSSA and MRSA.
T64054	Antibacterial agent 88
	Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.
T74715	Antibacterial agent 136
	Antibacterial Agent 136 (Compound 3), an oxadiazolone antibiotic, exhibits high antibacterial potency against Methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) 50 value of ...
T61624	Antibacterial agent 106
	Antibacterial agent 106 (compound 8) is a highly effective orally active antibacterial compound with antibiofilm activity. It demonstrates potent antibacterial effects against multi-drug resistant (MDR)-Gram-positive pat...

Compounds

Target: Others, Antibacterial

MAC-545496

T8507

Synonym:

Target: Antibacterial

Benzyldodecyldimethylammonium Chloride Dihydrate

T22269

Synonym:

Target: Antibacterial

Ceftobiprole medocaril

T40475

Synonym: BAL5788

Target: Antibacterial

Ceftobiprole

TQ0077

Synonym: Ro 63-9141,BAL 9141

Target: Antibacterial

Ceftaroline fosamil

T7387

Synonym: TAK-599,PPI0903

Target: Antibacterial, Antibiotic

Dalbavancin

T21358

Synonym: BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl

Target: Antibacterial, Antibiotic

Targocil

T4208

Synonym:

Target: Antibacterial

Glycosyltransferase-IN-1

T61037

Synonym:

Target: Others

Robenidine hydrochloride

T2549

Synonym: Rasexinium,Dexium,Robenidine Hydrochoride,Toraxine,Nugatex

Target: Antibacterial, Antibiotic, Parasite

Povidone iodine

T3114

Synonym: Betadine,Povidone-iodine,Isodine,PVP iodine,iodopovidone,PVP-I

Target: Antibacterial, Antibiotic

DETA NONOate

T36033

Synonym: NOC-18,Diethylamine NONOate

Target: DNA gyrase, Topoisomerase, Antibacterial

VP-4604

T64316

Synonym: 1-((4-Nitrophenyl)sulfonyl)piperidine

Target: MAO, Antibacterial, Antibiotic

Delpazolid

T4165

Synonym: LCB01-0371

Target: Antibacterial, Antibiotic

Antibacterial agent 139

Ceftaroline fosamil inner salt

T39816

Synonym: TAK-599 free acid,PPI0903freeacid

Target:

Antibacterial agent 104

Synonym: CP 5484,UNII-A53TMV6VUN,CP5484

Antibacterial agent 83

Synonym: CB 181963,CB181963,UNII-6784994L0W,CAB 175

Antibacterial agent 28

Synonym: NXL101,NXL-101,NXL 101

Antibacterial agent 163

Antibacterial agent 108

T74502

Synonym:

Target:

Antibacterial agent 165

T83097

Synonym:

Target:

Antibacterial agent 87

T64069

Synonym:

Target:

Contezolid acefosamil

T39230

Synonym: MRX-4,Contezolid acefosamil

Antibacterial agent 88

T64054

Synonym:

Target:

Antibacterial agent 136

T74715

Synonym:

Target:

Antibacterial agent 106

T61624

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T5724	Neogambogic acid	neo-gambogic acid	Apoptosis , Others , Antibacterial
	Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect, it may be responsible for the inhibition of proliferation of human breast cancer cell li...		Apoptosis , Others , Antibacterial
T1465	Mupirocin	Pseudomonic acid,BRL-4910A	DNA/RNA Synthesis , Antibacterial , Antibiotic
	Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T8148	Mupirocin calcium hydrate	Mupirocin calcium	Others , Antibacterial , Antibiotic
	Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria		Others , Antibacterial , Antibiotic
TN4943	Sanguisorbigenin	Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid	Antibacterial
	Sanguisorbigenin (Tomentosolic acid) is a natural antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA).		Antibacterial
TN1524	Continentalic acid		NOS , COX , Antibacterial , Prostaglandin Receptor
	Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including the Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin su...		NOS , COX , Antibacterial , Prostaglandin Receptor
TN2281	Sinapaldehyde	trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde	Antibacterial
	Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ...		Antibacterial
T8724	6-Methoxydihydrosanguinarine		Others
	6-Methoxydihydrosanguinarine is a natural product. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.It has antibacterial act...		Others
T3S0153	Xanthatin		Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
	1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T10838	Closthioamide		Antibacterial
	Closthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against MRSA, Ec, VRE, and Mv (MICs: 0.58 μM, 9.00 μM, 0.58 μM and 72.03 μM).		Antibacterial
T74200	Glicophenone
	Glicophenone, an antibacterial agent, demonstrates minimum inhibitory concentrations (MICs) of 32 μg/mL against multiple strains, including MRSA OM481, MRSA OM505, MRSA OM584, MRSA OM623, and MSSA 209P [1].
T2S0058	6-Ethoxychelerythrine	Ethoxychelerythrin	Antibacterial
	6-Ethoxychelerythrine (Ethoxychelerythrin) has anti-bacterial activity, it exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).		Antibacterial
TN4308	Isolupalbigenin		Antifection
	Isolupalbigenin shows promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 uM), it also shows in vitro inhibitory activity toward human glyoxalase I. Isolupalbigenin shows two different antibacter...		Antifection
TN2524	1-Acetyl-β-carboline	1-Acetyl-beta-carboline	Antifection
	Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.		Antifection
TN3216	(3R)-7,4’-Dihydrohomoisoflavanone	7,4'-Dihydroxyhomoisoflavanone	Antibacterial
	(3R)-7,4’-Dihydrohomoisoflavanone, a natural compound, exhibits potent antibacterial properties against both S. aureus and methicillin-resistant Staphylococcus aureus (MRSA).		Antibacterial
TN3907	Pinosylvin monomethyl ether	(E)-3-Hydroxy-5-methoxystilbene	Antifection
	(E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacil...		Antifection
T74206	Kalimantacin A
	Kalimantacin A, a potent antibiotic, exhibits effective antibacterial activity against Staphylococcus, including methicillin-resistant Staphylococcus aureus (MRSA) [1] [2].
TN1444	Bis(dihydrochelerythrinyl)amine	bis[6-(5,6-dihydrochelerythrinyl)]amine	Antifection
	BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).		Antifection
T73673	Thiomarinol A
	Thiomarinol A (4-Hydroxythiomarinol C), a potent antibiotic, is a hybrid compound comprising dithiolopyrrolone and marinolic acid, exhibiting antimicrobial activity. It effectively inhibits MRSA IleRS in a dose-dependent...
T73207	Laburnetin
	Laburnetin, an isoflavone antibacterial agent, exhibits antibacterial activity against fungi and S. vesicarium, and enhances the susceptibility of Methicillin-resistant Staphylococcus aureus (MRSA) strains to Methicillin...
T38349	Talaromycesone A
	Talaromycesone A is a fungal metabolite originally isolated fromTalaromyces.1It is active againstS. epidermidisand methicillin-resistantS. aureus(MRSA) bacteria (IC50s = 3.70 and 5.48 μM, respectively). Talaromycesone A ...
TN1814	Juncusol		Caspase , Antifection
	Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 cells. Juncusol has anti-microbial activity, it shows signific...		Caspase , Antifection
T75273	Teicoplanin sodium
	Teicoplanin sodium (Antibiotic MDL-507 sodium) is a potent lipoglycopeptide antibiotic . Teicoplanin sodium shows antiviral activity for HIV-1 , SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity [1] [2...
TN3450	Artanin		Antifection
	Artanin displays promising inhibition against both MSSA and MRSA with minimal inhibitory concentrations (MICs) of 8-64 ug/ml, but very weak against Gram-negative pathogen and yeast with MICs of 256 to ≥1024 ug/ml.		Antifection
TN4097	Gancaonin G		Antifection
	Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans.		Antifection
T79943	6-C-Methylquercetin-3,4'-dimethyl ether		Antibiotic
	6-C-Methylquercetin-3,4'-dimethyl ether is a flavonol derivative extracted from Bauhinia thonningii Schum leaves, displaying antibacterial effects on Gram-negative multidrug-resistant bacteria and methicillin-resistant S...		Antibiotic
T75555	(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol
	(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be isolated from the roots of Atractylodes japonica. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol h...
TN4319	Isopimaric acid		Antifection
	Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . Isopimaric acid is also poss...		Antifection
T75560	4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-
	4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2), a quinolone alkaloid extracted from Cnidium, demonstrates activity against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting minimum inhibitor...
TN6010	Picrasidine S
	Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria me...
T75278	Pristinamycin
	Pristinamycin, synthesized by Streptomyces pristinaespiralis, is an orally administered antibiotic resembling streptogramin, comprising two distinct components: Pristinamycin I (PI) and Pristinamycin II (PII). This compo...
T38394	PSMα3
	PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation ...
T75700	Longistyline A
	Longistyline A (Longistylin A), a natural stilbene extracted from the leaves of Cajanus cajan, exhibits antimicrobial activity with a minimum inhibitory concentration (MIC) value of 1.56 μg/mL against MRSA and demonstrat...
T36417	Nargenicin	Antibiotic 47444
	Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive...
T36000	3-Hydroxyterphenyllin
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,...

天然物製品

Neogambogic acid

T5724

Synonym: neo-gambogic acid

Target: Apoptosis, Others, Antibacterial

Mupirocin

T1465

Synonym: Pseudomonic acid,BRL-4910A

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Mupirocin calcium hydrate

T8148

Synonym: Mupirocin calcium

Target: Others, Antibacterial, Antibiotic

Sanguisorbigenin

TN4943

Synonym: Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid

Target: Antibacterial

Continentalic acid

TN1524

Synonym:

Target: NOS, COX, Antibacterial, Prostaglandin Receptor

Sinapaldehyde

TN2281

Synonym: trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde

Target: Antibacterial

6-Methoxydihydrosanguinarine

Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial

Protosappanin A

TJS1779

Synonym: PTA

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

Closthioamide

T10838

Synonym:

Target: Antibacterial

6-Ethoxychelerythrine

T2S0058

Synonym: Ethoxychelerythrin

Target: Antibacterial

Synonym: 1-Acetyl-beta-carboline

Target: Antifection

(3R)-7,4’-Dihydrohomoisoflavanone

TN3216

Synonym: 7,4'-Dihydroxyhomoisoflavanone

Target: Antibacterial

Pinosylvin monomethyl ether

TN3907

Synonym: (E)-3-Hydroxy-5-methoxystilbene

Bis(dihydrochelerythrinyl)amine

TN1444

Synonym: bis[6-(5,6-dihydrochelerythrinyl)]amine

Target: Caspase, Antifection

6-C-Methylquercetin-3,4'-dimethyl ether

T79943

Synonym:

Target: Antibiotic

(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol

4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-

Synonym: Antibiotic 47444

Target:

3-Hydroxyterphenyllin

T36000

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03532	ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. ClfB Protein, S. aureus (strain...
TMPH-03529	Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...

ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)

TMPH-03532

Species: Staphylococcus aureus

Expression System: E. coli

Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)

TMPH-03529

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

カタログ番号	製品名
L6610	Anti-infective Natural Product Library		1060 compounds
	A unique collection of 1060 species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Anti-infective Natural Product Library

L6610

Compounds: 1060