Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chamaejasmenin B is a compound isolated from Stellera chamaejasme L. Chamaejasmenin B has anticancer and antitumor activity, inhibiting cancer cell migration and invasion, and inhibiting tumor metastasis.Chamaejasmenin B is used in the study of cancers such as breast cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 176,000 |
5 mg | 在庫あり | ¥ 365,000 |
10 mg | 在庫あり | ¥ 493,500 |
25 mg | 在庫あり | ¥ 732,500 |
50 mg | 在庫あり | ¥ 984,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 438,500 |
説明 | Chamaejasmenin B is a compound isolated from Stellera chamaejasme L. Chamaejasmenin B has anticancer and antitumor activity, inhibiting cancer cell migration and invasion, and inhibiting tumor metastasis.Chamaejasmenin B is used in the study of cancers such as breast cancer. |
In vitro | Chamaejasmenin B exerted potent anti-proliferative effects in the 8 human solid tumor cell lines (HepG2, SMMC-7721, A549, MG63, U2OS, KHOS, HCT-116, and HeLa) with the IC50 values ranging from 1.08 to 10.8 μmol/L)) values ranged from 3.07 to 15.97 μmol/L). In the most sensitive A549 and KHOS cells, the mechanisms underlying the antiproliferative effects were characterized. The two compounds induced prominent expression of the DNA damage marker γ-H2AX as well as apoptosis. Furthermore, treatment of the cells with the two compounds caused prominent G(0)/G(1) phase arrest.[3] |
分子量 | 570.54 |
分子式 | C32H26O10 |
CAS No. | 89595-71-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Chamaejasmenin B 89595-71-1 Others Chamaejasmenin A Inhibitor inhibitor inhibit