Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 7,500 | |||
100 mg | 在庫あり | ¥ 11,000 | |||
200 mg | 在庫あり | ¥ 16,000 | |||
500 mg | 在庫あり | ¥ 26,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE. |
In vitro | Clofibric acid enhances the expression of carbonyl reductase in vivo, reduces PGE2 levels, and diminishes the quantity of vascular endothelial growth factor (VEGF) in OVCAR-3 tumors and DISS-origin ascites. In solid OVCAR-3 tumors, it decreases microvascular density and induces apoptosis. Compared to the control, a 9,000 ppm Clofibric acid diet significantly reduces the growth of OVCAR-3 tumor xenografts s.c. by 46% and notably prolongs the survival of mice with DISS-origin malignant ascites. |
In vivo | Clofibric acid enhances the expression of the CYP4A6 gene in RK13 cells transfected with PPAR-Gamma. |
別名 | Chlorofibrinic acid |
分子量 | 214.65 |
分子式 | C10H11ClO3 |
CAS No. | 882-09-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 40 mg/mL (186.3 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 45 mg/mL (209.64 mM)
You can also refer to dose conversion for different animals. 詳細
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Clofibric acid 882-09-7 DNA Damage/DNA Repair Metabolism PPAR Drug Metabolite Peroxisome proliferator-activated receptors Chlorofibrinic acid Inhibitor inhibit inhibitor