Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | お問い合わせ | |||
25 mg | 在庫あり | ¥ 10,000 | |||
50 mg | 在庫あり | ¥ 14,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,500 |
説明 | Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease. |
ターゲット&IC50 | TgPrxII:23 µM (IC50) |
分子量 | 347.99 |
分子式 | C10H8Br2N2O2 |
CAS No. | 18080-67-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 14.29 mg/mL (41.06 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Conoidin A 18080-67-6 Microbiology/Virology Parasite antioxidative antioxidant heart disease Inhibitor Peroxiredoxin II hyperperoxidation ischaemic inhibit neuroprotective inhibitor