Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 16,500 | |||
5 mg | 在庫あり | ¥ 26,000 | |||
10 mg | 在庫あり | ¥ 41,000 | |||
25 mg | 在庫あり | ¥ 76,500 | |||
50 mg | 在庫あり | ¥ 128,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist. |
In vitro | D-3263 hydrochloride binds and activates TRPM8, which may lead to increased entry of calcium and sodium; destruction of calcium and sodium homeostasis; induction of cell death in tumor cells expressing TRPM8. D-3263 hydrochloride may reduce the level of dihydrotestosterone (DHT), which may contribute to its inhibitory effect on prostate cancer and BPH[1]. |
別名 | EC D-3263 HCl, D3263 HCl salt |
分子量 | 409.95 |
分子式 | C21H32ClN3O3 |
CAS No. | 1008763-54-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 35 mg/mL (85.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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D-3263 hydrochloride 1008763-54-9 Membrane transporter/Ion channel TRP/TRPV Channel EC D-3263 HCl D3263 HCl salt D3263 Hydrochloride D-3263 Hydrochloride D3263 HCl D 3263 Hydrochloride Inhibitor inhibitor inhibit