Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 45,000 | |||
50 mg | 在庫あり | ¥ 84,000 | |||
100 mg | 在庫あり | ¥ 128,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,000 |
説明 | D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. |
ターゲット&IC50 | TSHR:11.6 μM(EC50) |
In vitro | D3-βArr stimulated β-Arr 1 translocation with an efficacy threefold greater than TSH. The EC50 for β-Arr 1 translocation by D3-βArr was 11.6 μM. D3-βArr (10 μM) increased the efficacy of TSH in the translocation of β-Arr 1 at a maximum of 5.1-fold over TSH alone. |
別名 | NCGC00379308 |
分子量 | 333.43 |
分子式 | C20H23N5 |
CAS No. | 662164-09-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (299.91 mM)
You can also refer to dose conversion for different animals. 詳細
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D3-βArr 662164-09-2 GPCR/G Protein TSH Receptor Thyroid-stimulating hormone Receptor D3-bArr Thyrotropin receptor inhibit D3-betaArr D3βArr Inhibitor D-3-βArr NCGC 00379308 NCGC00379308 NCGC-00379308 D3 βArr inhibitor