Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function
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5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 18,000 | |||
25 mg | 在庫あり | ¥ 35,500 | |||
50 mg | 在庫あり | ¥ 68,500 | |||
100 mg | 在庫あり | ¥ 98,500 | |||
200 mg | 在庫あり | ¥ 137,500 |
説明 | Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function |
In vitro | The action of diclofensine on peripheral neuronal adrenergic function was studied through tests of the blood pressure response to NE, tyramine, and phenylephrine (PE).?The blood pressure response to NE was enhanced and that to tyramine was decreased by diclofensine, as a result of its inhibitive action on peripheral neuronal amine uptake.?PE sensitivity was also enhanced by diclofensine as well as after a single dose of desmethylimipramine (DMI).?In contrast to the common opinion that PE does not interact with the neuronal uptake mechanism, the increase in PE-induced blood pressure response after diclofensine and DMI suggests that PE, a nonbiogenic amine, does indeed enter into the peripheral adrenergic neuron[1]. |
別名 | Ro 8-4650 hydrochloride |
分子量 | 358.69 |
分子式 | C17H18Cl3NO |
CAS No. | 34041-84-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 52 mg/mL (144.97 mM)
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Diclofensine hydrochloride 34041-84-4 GPCR/G Protein Neuroscience Others Dopamine Receptor SLC6A3 DAT Inhibitor Ro 8-4650 inhibit Diclofensine Diclofensine Hydrochloride Dopamine Transporter Ro 8-4650 Hydrochloride Ro 8-4650 hydrochloride inhibitor