|
T23965 |
DAT 582
|
DAT582,DAT-582 |
|
|
DAT 582 is a novel serotonin3 receptor antagonist. It is also an effective and long-lasting antiemetic agent |
|
T70527 |
DAT-230
|
|
|
|
DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230 -tr... |
|
T25290 |
DAT1
|
DAT-1,DAT 1 |
|
|
DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin. |
|
T7341 |
Diclofensine
|
Ro 8-4650 |
Dopamine Receptor
,
Monoamine Transporter
|
|
Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine. |
|
T22714 |
Decynium 22
|
|
Others
|
|
Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor |
|
T0322 |
Fipexide
|
|
Dopamine Receptor
,
AChR
|
|
Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is... |
|
T6414 |
Bisacodyl
|
Fenilaxan,Dulcolax,Brocalax |
Others
|
|
Bisacodyl (Fenilaxan) is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation. |
|
T70525 |
ARC39
|
|
|
|
ARC39 is acid sphingomyelinase inhibitor (IC50 =20 nM). |
|
T1871 |
GBR 12935 dihydrochloride
|
GBR12935,GBR-12935,GBR 12935 |
Dopamine Receptor
|
|
GBR 12935 dihydrochloride (GBR 12935) can induce the increase of the extracellular levels of dopamine to basal levels. |
|
T1993 |
J-147
|
J147 |
Epigenetic Reader Domain
,
Dopamine Receptor
,
Monoamine Oxidase
|
|
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate... |
|
T3526 |
Dasotraline hydrochloride
|
SEP-225289 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe... |
|
T39429 |
AHN 1-055 hydrochloride
|
3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride |
Dopamine Receptor
|
|
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM). |
|
T11087 |
DOV-216,303 Free Base
|
DOV-216303 |
Dopamine Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
|
|
T10758L |
Centanafadine hydrochloride
|
EB-1020 hydrochloride |
Dopamine Receptor
,
Serotonin Transporter
,
Adrenergic Receptor
,
Norepinephrine
|
|
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin... |
|
T7745 |
Diclofensine hydrochloride
|
Ro 8-4650 hydrochloride |
Others
,
Dopamine Receptor
|
|
Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function |
|
T2092 |
Amitifadine hydrochloride
|
DOV-21947 hydrochloride,EB-1010 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Norepinephrine
|
|
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). |
|
T69807 |
EGFR-IN-451
|
|
|
|
EGFR-IN-451 is an EGFR inhibitor, attenuating Ang II-induced Kidney Fibrosis. |
|
T7153 |
Vanoxerine dihydrochloride
|
GBR-12909 dihydrochloride,I893 dihydrochloride |
Dopamine Receptor
|
|
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM) |
|
T0991 |
Desipramine hydrochloride
|
NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 |
Dopamine Receptor
,
5-HT Receptor
,
Serotonin Transporter
,
Adrenergic Receptor
|
|
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt... |
|
T29534 |
ABT-925 fumarate dihydrate
|
ABT 925,LU201640,ABT925,ABT-925,BSF201640,DAT201 |
|
|
ABT-925 is a selective dopamine D3 receptor (DRD3) antagonist with an in vitro affinity approximately 100 times higher for dopamine D3 receptors than for D2 receptors. |
|
T23445 |
Anxiolytic/nonsedative agent-1
|
TCS 1205 |
GABA Receptor
|
|
Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α... |
|
T13110 |
Tedatioxetine hydrobromide
|
Lu AA 24530 hydrobromide |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
|
|
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) is a serotonin-norepinephrine-dopamine reuptake inhibitor and an antagonist of 5-HT2A, 5-HT2C, 5-HT3, and α1A-adrenergic receptors, which can be used to treat depress... |
|
T29645 |
Adatanserin hydrochloride
|
WY50324 hydrochloride |
5-HT Receptor
|
|
Adatanserin hydrochloride (WY50324 hydrochloride) is a novel 5-HT(1A)/5-HT(2) receptor ligand with potential neuroprotective effects and inhibition of ischemic efflux of endogenous amino acids, which can be used in the s... |
|
T1970 |
Gedatolisib
|
PF-05212384,PKI-587 |
PI3K
,
mTOR
|
|
Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signaling pathway. |
|
T19668 |
Tiomolibdate diammonium
|
Ammonium molybdenum sulfide,Ammonium tetrathiomolybdate,NSC 286644,ATTM,Coprexa |
Others
|
|
Tiomolibdate diammonium (NSC-286644) is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and ... |
|
T9901A-007 |
Datopotamab
|
|
Others
|
|
Datopotamab (CDP7657) is a TROP2-targeting antibody that is a naked antibody to Datopotamab deruxtecan and can be used to synthesize active antibody conjugators (Datopotamab deruxtecan). |
|
T23631 |
Adatanserin
|
WY-50324,WY 50324,WAY SEB 324,WY50324 |
5-HT Receptor
|
|
Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist with potential neuroprotective activity for the study of anxiety and depression. |
|
T7747 |
Datelliptium chloride hydrochloride
|
|
DNA/RNA Synthesis
|
|
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities. |
|
T15378L |
Gemcitabine elaidate hydrochloride
|
CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride |
Others
|
|
Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. In contrast to gemcitabine, G... |
|
T34795 |
Tedatioxetine
|
Lu AA 24530,Lu AA-24530,Lu AA24530 |
Dopamine Receptor
,
Serotonin Transporter
|
|
Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Tedatioxetine acts as a CYP2D6 substrate. |
|
T5159 |
Olodaterol hydrochloride
|
BI-1744 HCl,BI 1744 hydrochloride |
Adrenergic Receptor
|
|
Olodaterol hydrochloride (BI-1744 HCl) is a novel, long-acting β2-adrenergic agonist (EC50s: 97.7 nM for the human β2-adrenoceptor) that exerts its pharmacological effect by binding and activating β2-adrenergic receptors... |
|
T74398 |
DATPT
|
|
Reactive Oxygen Species
,
Antibacterial
|
|
DATPT is a small molecule 12WLVSKF17 peptide mimetic molecule.DATPT inhibits SNX9-p47phox interactions and inhibits the production of reactive oxygen species and inflammatory cytokines.DATPT has anti-inflammatory and ant... |
|
T39630 |
Zandatrigine
|
NBI-921352,XEN901 |
Sodium Channel
|
|
Zandatrigine (NBI-921352) is a blocker of sodium channel protein type 8 subunit alpha and can be used in studies about nervous system pathologies of epilepsy treatment. |
|
T22867 |
Indatraline hydrochloride
|
|
Others
|
|
Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) |
|
T75384 |
Cy5-dATP
|
|
|
|
Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] . |
|
T126401 |
Cordatin
|
|
|
|
Cordatin is a useful organic compound for research related to life sciences. The catalog number is T126401 and the CAS number is 110382-43-9. |
|
T70323 |
Diethanolamine Fusidate
|
|
|
|
Diethanolamine Fusidate is a bacteriostatic antibiotic with similar activity and better absorption after oral administration (in animals) than the sodium salt of Fusidic Acid. This product inhibits protein synthesis in p... |
|
T15378 |
Gemcitabine elaidate
|
Gemcitabine 5'-elaidate,Gemcitabine (elaidate),CO-101,CP-4126 |
Apoptosis
,
Nucleoside Antimetabolite/Analog
,
Autophagy
|
|
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracel... |
|
T16780 |
Rodatristat
|
KAR5417 |
Others
|
|
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively). |
|
T39121 |
Odatroltide
|
DHDMIQK(KAP),Odatroltide |
|
|
Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus. |
|
T76875 |
Zanidatamab
|
|
|
|
Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumor activity [1]. |
|
T77104 |
Obrindatamab
|
|
|
|
Obrindatamab, a humanized anti-B7-H3/CD3 bispecific antibody, targets B7-H3 and CD3, facilitating redirected cytotoxic T-lymphocyte (CTL) activity towards B7-H3-expressing cancer cells. It is utilized in cancer research ... |
|
T81033 |
TAT-P4-(DATC5)2
|
|
|
|
TAT-P4-(DATC5)2 is a potent peptide inhibitor targeting the PDZ domain of protein interacting with C kinase-1 (PICK1), exhibiting a high affinity with a dissociation constant (K_i) of 1.7 nM. This compound has demonstrat... |
|
T31385 |
Desethyl-etomidate
|
R28141,Etomidate acid,R-28141,R 28141 |
|
|
Desethyl-etomidate is a biochemical. |
|
T124428 |
Datumetine
|
|
|
|
Datumetine is a useful organic compound for research related to life sciences and the catalog number is T124428. |
|
T82717 |
Cis-Indatraline hydrochloride
|
cis-Lu 19-005 |
|
|
Cis-indatraline hydrochloride (cis-Lu 19-005) is an active compound utilized in the research of neurodegenerative diseases [1]. |
|
T73265 |
Tolindate
|
|
|
|
Tolindate, a potent PXR agonist, demonstrates antifungal activity and possesses an EC50 value of 8.3 µM. |
|
T24458 |
Methyl acetimidate
|
|
|
|
Methyl acetimidate is an effective in vitro antisickling agent. It has few detrimental effects on the red cell. |
|
T7429 |
Datelliptium chloride
|
|
DNA/RNA Synthesis
|
|
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities. |
|
T38630 |
Ludaterone
|
|
|
|
Ludaterone is an antiandrogen agent, with potent antiandrogenic activity. |
