Powder: -20°C for 3 years | In solvent: -80°C for 1 year
E-7386 is an oral active CBP/ -catenin modulator.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 20,500 | |||
5 mg | 在庫あり | ¥ 62,000 | |||
10 mg | 在庫あり | ¥ 94,000 | |||
25 mg | 在庫あり | ¥ 156,500 | |||
50 mg | 在庫あり | ¥ 222,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 96,500 |
説明 | E-7386 is an oral active CBP/ -catenin modulator. |
In vivo | E-7386 is an oral active CBP/ -catenin regulator, which can induce T cells to infiltrate into the tumor in the Wnt1 tumor cogene mouse model and enhance the anti-tumor activity of anti-PD-1 monoclonal antibody.In the Wnt1 model, t-cell infiltration in the vehicle control group was limited, while t-cell infiltration in the E-7386 treatment group was obvious, and E-7386 showed significant anti-tumor activity. |
別名 | E7386 |
分子量 | 725.85 |
分子式 | C39H48FN9O4 |
CAS No. | 1799824-08-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: 250 mg/mL (344.42 mM), Sonication is recommended.
DMSO: 125 mg/mL (172.21 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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E-7386 1799824-08-0 Chromatin/Epigenetic Epigenetic Reader Domain E7386 inhibit Inhibitor E 7386 inhibitor