Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
説明 | Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT). |
ターゲット&IC50 | COMT:151 nM |
In vivo | In various tissues, such as the liver, duodenum, kidney, and lung, Entacapone inhibits the activity of catechol-O-methyltransferase (COMT). Additionally, in PC12 cells, Entacapone can suppress extracellular cytotoxicity induced by the aggregation of α-syn and β-amyloid (Aβ). |
別名 | OR-611 |
分子量 | 305.29 |
分子式 | C14H15N3O5 |
CAS No. | 130929-57-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (163.78 mM)
Ethanol: 2 mg/mL (6.55 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Entacapone 130929-57-6 Metabolism Transferase OR-611 COMT OR 611 metabolic disorder inhibit OR611 Inhibitor ?FTO?knockdown Parkinson's disease inhibitor