Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively.
説明 | Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity. Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. |
ターゲット&IC50 | EGFR:1.48 nM, HER2:7.15 nM, HER4:2.49 nM |
別名 | S-22611 hydrochloride |
分子量 | 596.48 |
分子式 | C30H28Cl2FN5O3 |
CAS No. | 2071195-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (209.56 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Epertinib hydrochloride 2071195-74-7 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR HER inhibit Epidermal growth factor receptor S22611 Epertinib Epertinib Hydrochloride ErbB-1 HER1 S22611 Hydrochloride S 22611 S-22611 hydrochloride S-22611 S 22611 Hydrochloride S-22611 Hydrochloride Inhibitor inhibitor