Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FzM1.8 is an allosteric FZD4 agonist with a pEC50 of 6.4. FzM1.8 binds to FZD4, promotes TCF/LEF transcriptional activity in the absence of any WNT ligand, and activates the WNT/β-catenin pathway.
説明 | FzM1.8 is an allosteric FZD4 agonist with a pEC50 of 6.4. FzM1.8 binds to FZD4, promotes TCF/LEF transcriptional activity in the absence of any WNT ligand, and activates the WNT/β-catenin pathway. |
ターゲット&IC50 | Fzm1.8:(pEC50)6.4 |
分子量 | 322.31 |
分子式 | C18H14N2O4 |
CAS No. | 2204290-85-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 76.5 mg/mL (237.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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FzM1.8 2204290-85-5 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin FzM-1.8 Inhibitor inhibitor inhibit