Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.
説明 | MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. |
In vivo | MSAB act against Wnt/β-catenin signaling and identified ?as a selective inhibitor of Wnt/β-catenin signaling.?MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models.?MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.?might represent an effective therapeutic strategy for cancers addicted to the Wnt/β-catenin signaling pathway. |
分子量 | 305.35 |
分子式 | C15H15NO4S |
CAS No. | 173436-66-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (90.06 mM)
You can also refer to dose conversion for different animals. 詳細
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MSAB 173436-66-3 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin anti-tumor Wnt inhibit degradation β-catenin Inhibitor Beta catenin cancer inhibitor