Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.
説明 | BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor. |
ターゲット&IC50 | Wnt:700 nM (EC50) |
In vitro | BML-284 HCL does not inhibit the activity of GSK-3β, and may be a useful tool in the study of physiological processes that involve the Wnt pathway. |
In vivo | In a Xenopus model, Wnt agonist 1 (10 μM) mimics the effects of Wnt at the whole-organism level, and affects Xenopus embryonic head specification. |
別名 | BML-284 HCL, Wnt agonist 1 HCL |
分子量 | 386.84 |
分子式 | C19H19ClN4O3 |
CAS No. | 2095432-75-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9 mg/mL (23.27 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BML-284 hydrochloride 2095432-75-8 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin BML284 hydrochloride AGS TCF BML-284 HCL N-cadherin Wnt agonist 1 HCL Wnt BML284 cardiac defect MNK45 BML 284 BML284 Hydrochloride BML-284 E-cadherin malformed phenotype BML 284 Hydrochloride inhibit Inhibitor BML-284 Hydrochloride BML 284 hydrochloride inhibitor