Powder: -20°C for 3 years | In solvent: -80°C for 1 year
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation.
説明 | G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation. |
In vitro | Continuous administration of G418 at doses ranging from 40 to 80 mg/kg for three consecutive days is sufficient to eradicate all untransfected Brucella bacterium parasites in infected mice. |
In vivo | At concentrations ranging from 1 to 300 micrograms/ml, G418 inhibits a variety of prokaryotic and eukaryotic organisms. Typically, concentrations of 5 mg/L or lower are effective against bacteria and algae, while a concentration of 400 mg/L is used for the selection of mammalian cells, and a maintenance concentration for mammalian cells is set at 200 mg/L. |
別名 | Geneticin, G418 Sulfate, Antibiotic G-418 sulfate, Geneticin sulfate |
分子量 | 692.71 |
分子式 | C20H40N4O10·2H2O4S |
CAS No. | 108321-42-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 43.31mM
DMSO: Insoluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
G-418 disulfate 108321-42-2 Microbiology/Virology Antibiotic Antibacterial synthesis eukaryotic Antibiotic G-418 Geneticin Sulfate G418 Antibiotic G 418 Antibiotic G418 Sulfate Antibiotic G418 Geneticin Bacterial Antibiotic G 418 Sulfate Inhibitor G 418 Sulfate protein G 418 disulfate inhibit G418 Sulfate G-418 Antibiotic G-418 sulfate G-418 Disulfate cells G 418 Antibiotic G-418 Sulfate G418 disulfate Geneticin sulfate G418 Disulfate G 418 Disulfate G-418 Sulfate inhibitor