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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T9978 | Glutathione synthesis-IN-1 | Others | |
Glutathione synthesis-IN-1 (DC-1) is a inhibitor of glutathione synthesis[1]. | |||
T82944 | ATP Synthesis-IN-2 | ||
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.7 μg/mL against Pseudomonas aeruginosa (PA) [1]. | |||
T82945 | ATP Synthesis-IN-1 | ||
ATP Synthesis-IN-1 (Compound 4), a quinoline derivative, potently inhibits PA ATP synthesis with an IC50 of 11.1μg/mL and exhibits antibacterial properties. This compound is utilized in studying drug-resistant PA infecti... | |||
T36757 | DMT-dU-CE Phosphoramidite | DNA/RNA Synthesis | |
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA. | |||
TP1115 | L-Asparaginase | L-ASNase | Others |
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a... | |||
T20700 | Racemetirosine | Others | |
Racemetirosine is an inhibitor of Tyrosine 3-monooxygenase, and consequently it inhibits the synthesis of catecholamines. | |||
T14522 | Beaucage reagent | DNA/RNA Synthesis | |
Beaucage reagent, which is found to be effective in causing DNA cleavage. | |||
T36756 | DMT-dG(ib) Phosphoramidite | DNA/RNA Synthesis | |
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA. | |||
T12019 | Methylproamine | Others | |
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA. | |||
T6801 | CeMMEC13 | Carboxypeptidase , DNA/RNA Synthesis | |
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM). | |||
T1154 | Rifaximin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... | |||
T15611 | JH-RE-06 | DNA/RNA Synthesis | |
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact... | |||
T8003 | Methotrexate disodium | Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate | |
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor | |||
T3279 | Silver sulfadiazine | Silvadene,Dermazin,Flamazine | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity. | |||
T2037 | TH588 | DNA/RNA Synthesis , MTH1 | |
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells. | |||
T8955 | PCNA-I1 | Others | |
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer. | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T2100 | CX-5461 | DNA/RNA Synthesis | |
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA. | |||
T36687 | Ac-rC Phosphoramidite | Nucleoside Antimetabolite/Analog | |
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides. | |||
T5637 | Triflumuron | Others | |
Triflumuron is an insecticide belonging to the group of so-called insect growth regulators. It inhibits the synthesis of chitin by the insect larvae, causing the die. | |||
T40168 | DHODH-IN-16 | Dehydrogenase | |
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human). | |||
T2410 | Nedaplatin | NSC 375101D | DNA/RNA Synthesis |
Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand... | |||
T8873 | Bractoppin | Others , DNA/RNA Synthesis | |
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi... | |||
T40192 | DGTP | 2'-Deoxyguanosine-5'-triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. | |||
T15235 | Enocitabine | Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis | |
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ... | |||
T5639 | Lufenuron | Fluphenacur | Parasite |
Lufenuron (Fluphenacur) is a chitin-synthesis inhibitor. | |||
T7747 | Datelliptium chloride hydrochloride | DNA/RNA Synthesis | |
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities. | |||
T14501 | BAY-2402234 | Dehydrogenase , DNA/RNA Synthesis | |
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity. | |||
T35648 | 4-Thiouridine | Others | |
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl... | |||
T1233 | Oxolinic acid | Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox | Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS. | |||
T38237 | 2′-O-Methylcytidine | Nucleoside Antimetabolite/Analog , HCV Protease | |
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G.... | |||
T16703 | Quarfloxin | CX-3543 | DNA/RNA Synthesis |
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-... | |||
T11020 | DHODH-IN-11 | Dehydrogenase , DNA/RNA Synthesis | |
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | |||
T40661 | ML-60218 | DNA/RNA Synthesis | |
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms. | |||
T4345 | CeMMEC1 | CeMMEC1 HCl | Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis |
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM). | |||
T10384 | Farudodstat | ASLAN003 | Apoptosis , Dehydrogenase , DNA/RNA Synthesis |
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML. | |||
T9103 | BVDV-IN-1 | DNA/RNA Synthesis | |
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to... | |||
T10411 | AU1235 | Antibacterial | |
T8747 | Levofloxacin hydrochloride | DNA gyrase , Topoisomerase | |
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh... | |||
T13659 | DMTr-LNA-5MeU-3-CED-phosphoramidite | Nucleoside Antimetabolite/Analog | |
DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside. | |||
T1349 | 5-Fluorouridine | Others , DNA/RNA Synthesis | |
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound... | |||
T9121 | AG-636 | Dehydrogenase , DNA/RNA Synthesis | |
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects. | |||
T12438 | PfDHODH-IN-1 | Dehydrogenase , Parasite | |
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity. | |||
T39785L | TH5427 | NUDIX hydrolase | |
TH5427 is a lead NUDT5 inhibitor(MG assay IC50 = 29 nM). | |||
T8354 | Triazavirin | Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis | |
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. | |||
T11546 | HDHODH-IN-1 | Dehydrogenase | |
T2069L | TH287 hydrochloride | DNA/RNA Synthesis , MTH1 | |
TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts. | |||
T7088 | Diflubenzuron | Dimilin,Difubenzuron,Larvakil,Difluron | P450 |
Diflubenzuron (Larvakil) is a benzoyl-urea insecticide, found to be a potent inhibitor of melanosome synthesis in mouse melanoma cells. Diflubenzuron has also been shown to inhibit TCDD-induced CYP1A1 expression in HepG2... | |||
T6357 | (S)-crizotinib | ent-crizotinib | Apoptosis , DNA/RNA Synthesis , MTH1 |
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib. | |||
T1846 | Y-320 | Y320 | IL Receptor , Lipase , Interleukin |
Y-320 is a new phenylpyrazoleanilide immunomodulator. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7520 | Deoxycytidine triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite | |
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. | |||
T13969 | Xanthopterin (hydrate) | Others , DNA/RNA Synthesis | |
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species. | |||
T40179 | Sodium Camptothecin | DNA/RNA Synthesis | |
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i... | |||
T2S1635 | 3-Isomangostin | MTH1 | |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac... | |||
T21498 | Phleomycin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix. | |||
TN1134 | Euscaphic acid | Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor | |
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of... | |||
T5270 | 5-Methylcytosine | Others , DNA/RNA Synthesis , Endogenous Metabolite | |
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated... | |||
T5901 | 3-Hydroxy-2-methylpyridine | Others | |
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors. | |||
T37101 | 1-Hydroxyanthraquinone | DNA/RNA Synthesis | |
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response. | |||
TQ0184 | Chebulinic acid | ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad | |
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity. | |||
T7992 | 4-Hydroxyflavanone | NO Synthase | |
4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects | |||
T35455 | N-Nitrosodiethylamine | Diethylnitrosamine,NDEA | DNA/RNA Synthesis |
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso... | |||
T7529 | Yamogenin | Others | |
Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek. | |||
T6S0232 | Eriodictyol | Huazhongilexone | Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite |
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3.... | |||
T1068 | Dithranol | 1,8,9-trihydroxyanthracene,cignoline,Anthralin | Others , DNA/RNA Synthesis |
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS. | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T20945 | 2,4-D | Hedonal,Macondray,2,4-D acid,Chloroxone | DNA/RNA Synthesis |
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti... | |||
T16674 | Pseudouridine | Endogenous Metabolite | |
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure. | |||
T13229 | Tunicamycin | Influenza Virus , Antibacterial , Antibiotic , Antifungal | |
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity... | |||
TN1637 | Eurycomalactone | Anti-infection , NF-κB | |
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-in... | |||
TN2132 | Quinizarin | 1,4-Dihydroxyanthraquinone | Others , DNA/RNA Synthesis , Antifungal |
Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product | |||
T2998 | Dihydromyricetin | Ampelopsin,Ampeloptin | Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy |
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy... | |||
T4593 | ISOPIMPINELLIN | 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen | Antiviral , DNA/RNA Synthesis , Parasite |
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity. | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T0950 | Neomycin sulfate | Framycin sulfate | Phospholipase , ribosome , Antibacterial , Antibiotic |
Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prok... | |||
T1032 | Erythromycin | E-Mycin | ribosome , Antibacterial , Antibiotic |
Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity. | |||
T8244 | Raspberry ketone glucoside | Others | |
Raspberry ketone glucoside is a natural product in raspberry fruit, has lasting effects for the inhibition of melanogenesis and various melanogenic factors after the degradation in the skin. | |||
T13791 | N2-methylguanine | DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial | |
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside. | |||
T0895 | Oxytetracycline | Terramycin | ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. | |||
T0064 | Adenine | Vitamin B4,6-Aminopurine | DNA/RNA Synthesis , Endogenous Metabolite , AChR |
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic... | |||
TWP2911 | Thymidine | 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin | Others , DNA/RNA Synthesis , Endogenous Metabolite |
1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues. | |||
T6758 | Anisomycin | Flagecidin,NSC 76712,Wuningmeisu C | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK |
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | |||
T7004 | Tubercidin | Sparsomycin A,7-Deazaadenosine | Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib... | |||
T6116 | Bleomycin Sulfate | Blenoxane,NSC125066 | DNA/RNA Synthesis , Antibiotic |
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity. | |||
T12045 | (-)-Hydroxycitric acid lactone | Garcinia lactone | ATP Citrate Lyase |
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, which catalyzes the extramitochondrial cleavage of citrate to oxaloac... | |||
TN1097 | β-Boswellic acid | Beta-boswellic acid | Lipoxygenase , DNA/RNA Synthesis |
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities. | |||
T7174 | Urolithin A | Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite | |
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties. | |||
T3343 | 5-methoxyflavone | 5-methoxy-2-phenylchromen-4-one | DNA/RNA Synthesis |
5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities. | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
T38427 | DUTP trisodium | 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate | DNA/RNA Synthesis |
dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR. | |||
T1465 | Mupirocin | Pseudomonic acid,BRL-4910A | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci. | |||
T7094 | Levomefolic Acid | 5-MTHF | Reactive Oxygen Species , Endogenous Metabolite |
Levomefolic Acid (5-MTHF) is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. Levomefolinic acid is used a... | |||
T6567 | Levofloxacin | Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin | Topoisomerase , Antibacterial , Antibiotic |
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. | |||
T14193 | α-Galactosylceramide | KRN7000,α-GalCer | Others |
α-Galactosylceramide (KRN7000) is a synthetic glycolipid with antitumorial and immunostimulatory and is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide and CD1d can bind ... | |||
T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T8148 | Mupirocin calcium hydrate | Mupirocin calcium | Others , Antibacterial , Antibiotic |
Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria | |||
T6624 | Oxytetracycline Dihydrate | Terramycin Dihydrate | Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | |||
T6225 | Adenine hydrochloride | Adenine HCl,6-Aminopurine hydrochloride | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry. | |||
T0687 | Simvastatin | MK-0733,MK 733 | Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy |
Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc... | |||
T0974 | Novobiocin Sodium | Albamycinsodium,Cathomycin,Albamycin | Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy |
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim... | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-03221 | Intrinsic Factor Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the ... | |||
TMPH-00711 | BioH Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of th... | |||
TMPH-00007 | HMGCR Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol ... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPY-00545 | Dermcidin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia... | |||
TMPY-02483 | ATP citrate lyase/ACLY Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP... | |||
TMPY-03650 | BirA Protein, E. coli, Recombinant (His & MBP) | E. coli | E. coli |
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these prote... | |||
TMPY-01101 | Coagulation factor X/F10 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the... | |||
TMPH-00608 | Dihydrofolate reductase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-03535 | Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed... | |||
TMPH-01211 | DGUOK Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis de... | |||
TMPH-03714 | HAS1 Protein, Xenopus tropicalis, Recombinant (His & Myc) | Xenopus tropicalis | E. coli |
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role ... | |||
TMPH-01224 | Dihydrofolate reductase Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds... | |||
TMPH-02383 | Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP35 Protein (His) | MARV | E. coli |
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. | |||
TMPH-03581 | Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) | Staphylococcus epidermidis | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed ... | |||
TMPH-01561 | ISCU Protein, Human, Recombinant (His & Myc) | Human | Baculovirus Insect Cells |
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic Functions as a cytoplasmic scaffold protein for the de... | |||
TMPH-00663 | APT Protein, E. coli O139:H28, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | |||
TMPY-06416 | SARS-CoV-2 NSP8 Protein | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPJ-00937 | RRM2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. S... | |||
TMPH-03432 | ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) | Saccharomyces cerevisiae | E. coli |
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle... | |||
TMPH-03431 | ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) | Saccharomyces cerevisiae | E. coli |
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle... | |||
TMPH-00515 | PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO) | Entamoeba histolytica | E. coli |
Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. | |||
TMPH-03055 | Ribonuclease mitogillin Protein, Neosartorya fumigata, Recombinant (His & Myc & SUMO) | Neosartorya fumigata | E. coli |
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. | |||
TMPH-01584 | KRT7 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). | |||
TMPY-05749 | SARS-CoV-2 NSP8 Protein (Avi) | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPH-00171 | PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO) | Bacillus subtilis | E. coli |
Probably involved in peptidoglycan modification during cortex synthesis. PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecula... | |||
TMPK-00958 | BTN1A1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition. | |||
TMPY-03605 | Glutaredoxin 1/GRX1 Protein, Human, Recombinant (His) | Human | E. coli |
Glutaredoxin-1, also known as GRX1 and GLRX, belongs to theglutaredoxin family. Glutaredoxinsare smallredoxenzymes that useglutathioneas a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatica... | |||
TMPH-00529 | UvsY Protein, Enterobacteria phage T4, Recombinant (Avi & His) | Enterobacteria phage T4 | E. coli |
Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA. | |||
TMPJ-01257 | PMM1 Protein, Human, Recombinant (His) | Human | E. coli |
Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. G... | |||
TMPY-05024 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His) | ZIKV | Baculovirus Insect Cells |
Zika virus NS5 is involved in methytransferase and RNA guanylytransferase activities and capping and synthesis of RNA. And, NS5 is also an RNA-dependent RNA polymerase. | |||
TMPH-01085 | CHAT Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. CHAT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic... | |||
TMPH-03524 | KAS III Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may ther... | |||
TMPJ-00905 | DTYMK Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolis... | |||
TMPH-00422 | Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) | Clostridium symbiosum | E. coli |
Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) is expr... | |||
TMPH-00131 | Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) | Aspergillus restrictus | E. coli |
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) is exp... | |||
TMPK-01386 | TK1 Potein, Canine, Recombinant (His) | Canine | E. coli |
Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phas... | |||
TMPH-03044 | PBP1a Protein, MenB, Recombinant (His & SUMO) | MenB | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-... | |||
TMPH-02568 | CTGF/CCN2 Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types ... | |||
TMPH-02882 | NQO2 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma... | |||
TMPH-00578 | NrdD Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag.... | |||
TMPH-03595 | APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) | Streptococcus pyogenes | P. pastoris (Yeast) |
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) is expressed in yeast with N-10xHis an... | |||
TMPH-00157 | Thymidylate kinase Protein, Bacillus anthracis, Recombinant (His) | Bacillus anthracis | E. coli |
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. Thymidylate kinase Protein, Bacillus anthracis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. T... | |||
TMPH-00028 | Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) | AAV-2 | E. coli |
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a... | |||
TMPJ-01444 | IL-17A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it ... | |||
TMPH-02717 | HMGCS1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis. HMGCS1 Protein, Mouse, Recombinant (H... | |||
TMPK-01308 | TAG-72 Protein, Canine, Recombinant (His) | Canine | E. coli |
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA... | |||
TMPH-00015 | Abrin-d Protein, Abrus precatorius, Recombinant (His & Myc) | Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.; The B chain is a galactose-specific lectin th... | |||
TMPJ-00686 | B4GALT3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Beta-1,4-galactosyltransferase 3 (B4GALT3) belongs to the glycosyltransferase 7 family. It is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moie... | |||
TMPJ-01408 | HDGFRP3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 ... | |||
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カタログ番号 | 製品名 | ||
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L7810 | High Solubility Polyfunctional Group Fragment Library | 1159 compounds | |
Highly soluble multifunctional fragment library contains 1159 kinds of fragment molecules. | |||
L2510 | Lipid Metabolism Compound Library | 492 compounds | |
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L5500 | Toxic Compound Library | 262 compounds | |
A unique collection of 262 toxic substances for high throughput screening (HTS) and high content screening (HCS); | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L9001 | Food Additive Library | 425 compounds | |
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L8100 | Cell Cycle Compound Library | 677 compounds | |
A unique collection of 677 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L7900 | Osteogenesis Compound Library | 317 compounds | |
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening; | |||
L9600 | Peptide Compound Library | 791 compounds | |
791 peptides can be used in peptide drug development and signaling transduction and mechanism study; | |||
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); | |||
L6030 | Natural Product Derivatives Library for CADD | 163000 compounds | |
Large quantity: contains 163,000 natural product derivatives and the number is continuously updating; | |||
L9300 | Macrocyclic Compound Library | 210 compounds | |
210 macrocyclic compounds of known activity for high-throughput, high-content screening; |