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カタログ番号	製品名	別名	ターゲット
T22774L	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
TP2247	eukaryotic translation initiation factor 3		Others
	Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. Eukaryotic translation initiation factor 3 binds to the ribosome subunit-mRNA complex. It has been implicated i...		Others
T22774	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ...		Others
T1742	4E1rcat		PERK , Autophagy
	4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.		PERK , Autophagy
T11375	GCN2iB		Others , Autophagy
	GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM.		Others , Autophagy
T14044	4E2RCat		PERK
			PERK
T11374	GCN2-IN-6		Others , PERK
			Others , PERK
T2665	4EGI-1	4EGI 1	Apoptosis , PERK , Autophagy
	4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).		Apoptosis , PERK , Autophagy
T21508	Anhydrotetracycline hydrochloride		Antibacterial , Antibiotic
	Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.		Antibacterial , Antibiotic
T3207	Briciclib	ON 014185	CDK , PERK , Autophagy
	Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.		CDK , PERK , Autophagy
T11373	GCN2-IN-1	A-92	Others
	GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.		Others
T9149	2BAct	2B-Act,2B Act	PERK
	2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response		PERK
T5173	SBI-0640756	SBI 0640756,SBI-756	PERK , Autophagy
	SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.		PERK , Autophagy
T28506	Rbin-2		Phosphatase
	Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study...		Phosphatase
T67945	WAY-620473		PARP
	WAY-620473 is a potent PARP-1 inhibitor with antitumor activity and alters eukaryotic lifespan.		PARP
T62461	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine		Others
	Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine can be used to alter eukaryotic lifespan.		Others
T22592	ATPγS tetralithium salt	ATP-gamma-S tetralithium salt	PERK
	ATPγS tetralithium salt is a substrate for nucleotide hydrolysis and RNA unraveling activity of the eukaryotic translation initiation factor eIF4A, associated with p97 mutants and prions.		PERK
TQ0137	A-484954	A 484954	CaMK , Parasite , Autophagy
	A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.		CaMK , Parasite , Autophagy
T7411	Rbin-1	Ribozinoindole-1	ATPase , Phosphatase
	Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.		ATPase , Phosphatase
T28543	RK-9123016	RK9123016,RK 9123016	Sirtuin
	RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer ce...		Sirtuin
T15790	Lucifer Yellow CH dilithium salt
	Lucifer Yellow CH dilithium salt is a fluorescent dye that can be commonly used for selective staining and the study of photodynamic disruption of eukaryotic and subcellular structures.
T11372	GC7 Sulfate		Autophagy
	GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS act...		Autophagy
T3045	Salubrinal		Apoptosis , Phosphatase , PERK , Autophagy , HSV
	Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).		Apoptosis , Phosphatase , PERK , Autophagy , HSV
T15735	Leptomycin B	CI 940,LMB	CRM1 , Antibiotic , Antifungal
	Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...		CRM1 , Antibiotic , Antifungal
TP1875L	CDK2 acetate(255064-79-0 free base)		Others
	CDK2 acetate is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.		Others
T39965	NF-κΒ activator 1		NF-κB
	NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferation and cell survival. NF-κΒ activator 1 induces superoxide ...		NF-κB
T38889	Thailanstatin A
	Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 =650 nM). Thailanstatin A inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the s...
T27544	Hippuristanol
	Hippuristanol is a potent steroid inhibitor of eukaryotic initiation factor 4A (eIF4A).
T10848	CMLD012073		Others
			Others
T34033	Phosphohistidine	3-Phosphohistidine
	Phosphohistidine is a eukaryotic enzyme dephosphorylating proteins and peptides.
T10847	CMLD012072		Others
	CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.		Others
T69376	Viriditoxin
	Viriditoxin is a secondary metabolite isolated from Aspergillus viridinutans that has been shown to inhibit FtsZ, the bacterial homologue of eukaryotic tubulin.
T11171	EIF4A3-IN-2		Others
	eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.		Others
T32537	LAI-1	LAI 1,Legionella autoinducer-1,Legionella autoinducer 1
	LAI-1 is a regulator of bacterial signaling, modulating gene regulation and cellular responses of eukaryotic cells (amoebae or macrophages) and a variety of processes including pathogen-host cell interactions.
T38766	Histone H3 (1-35)	Histone H3 (1-35)
	Histone H3 (1-35) is a 35-residue peptide derived from histone H3, which is a key member of the five main histones participating in the formation of chromatin within eukaryotic cells.
T19306	ELX-02 disulfate	NB-124 disulfate	Others
	ELX-02 disulfate (also referred to as NB-124 disulfate) is a synthetic eukaryotic ribosome selective glycoside (ERSG). This compound is currently in development as a therapy specifically designed to address genetic disea...		Others
T10849	CMLD012612		Others
			Others
T32126L	Hypusine HCl	(+)-Hypusine dihydrochloride,Hypusine dihydrochloride
	Hypusine HCl is an unusual amino acid found in all eukaryotes and in some archaea, but not in bacteria. The only known protein containing hypusine is eukaryotic translation initiation factor 5A (eIF5A) and a similar prot...
T26973	Cefatrizine	Cephatriazine,BL-S-640,BLS640,S 640P,BL S 640
	Cefatrizine is an inhibitor of eukaryotic elongation factor-2 kinase, a unique calcium/calmodulin-dependent protein kinase, is well known to regulate apoptosis, autophagy and ER stress in many types of human cancers.
T40210	EIF4E-IN-3	eIF4E-IN-3
	eIF4E-IN-3 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e), exhibiting noteworthy potential for investigating eIF4e dependent diseases, particularly cancer research (WO2021003157A1, compound 48...
T70790	Pateamine A
	Pateamine A is a marine macrolide that is isolated from the sponge Mycale hentscheli and exhibits anticancer and antiviral properties. It has a role as a marine metabolite, an antiviral agent, an antineoplastic agent, an...
T71815	TX-1918
	TX-1918 is a cell-permeable tyrphostin derivative that inhibits eukaryotic elongation factor-2 kinase (eEF-2K). TX-1918 disrupts the proliferation of HepG2 and HCT116 tumor cells.
T19307	ELX-02 sulfate	NB-124 sulfate	Others
	ELX-02 sulfate, also known as NB-124 sulfate, is a novel compound currently under development as a therapeutic agent for genetic diseases triggered by nonsense mutations. This investigational compound, an advanced synthe...		Others
T39530	EIF4A3-IN-5	eIF4A3-IN-5
	eIF4A3-IN-5 is a highly effective inhibitor of eukaryotic initiation factor 4A (eIF4A), specifically targeting eIF4AI and eIF4AII. With its potent inhibitory properties, eIF4A3-IN-5 shows great potential for advancing re...
T40214	EIF4E-IN-2	eIF4E-IN-2
	eIF4E-IN-2 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e). This compound exhibits significant potential in the investigation of eIF4e dependent diseases, particularly in the context of cancer ...
T16945	Streptolydigin	Portamycin	Antibacterial
	Streptolydigin inhibits RNA synthesis by binding to RNA polymerase and does not inhibit eukaryotic RNA polymerases. Streptolydigin is a 3-acetyltetramic acid antibiotic and a potent bacterial RNA polymerase inhibitor (Ki...		Antibacterial
T36750	Didesmethylrocaglamide
	Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects, with an IC50 of 5 nM. It hinders several growth-promoting si...
TP1875	CDK2
	CDK2, a eukaryotic S/T protein kinase family member, catalyzes the phosphoryl transfer from ATP γ-phosphate to the hydroxyl of serine or threonine (denoted as S0/T0) in a protein substrate.
T31616	ELX-02	NB-124,NB 124,NB124,ELX02,ELX 02
	ELX-02, also known as NB-124, is a eukaryotic ribosomal selective glycoside (ERSG) designed to increase the read-through activity in patients with nonsense mutations and enable the production of sufficient amounts of ful...
T15136L	DiZPK Hydrochloride (1337883-32-5 free base)	DiZPK Hydrochloride	Others
	DiZPK Hydrochloride is a structural analog of pyrrolysine (Pyl), acting as a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.		Others

Compounds

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

T22774L

Synonym:

Target: Others

eukaryotic translation initiation factor 3

TP2247

Synonym:

Target: Others

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

Target: PERK, Autophagy

GCN2iB

T11375

Synonym:

Target: Others, Autophagy

Target: Apoptosis, PERK, Autophagy

Anhydrotetracycline hydrochloride

T21508

Synonym:

Target: Antibacterial, Antibiotic

Briciclib

T3207

Synonym: ON 014185

Target: CDK, PERK, Autophagy

Synonym: 2B-Act,2B Act

Target: PERK

SBI-0640756

T5173

Synonym: SBI 0640756,SBI-756

Target: PERK, Autophagy

Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine

T62461

Synonym:

Target: Others

ATPγS tetralithium salt

T22592

Synonym: ATP-gamma-S tetralithium salt

Target: CaMK, Parasite, Autophagy

Rbin-1

T7411

Synonym: Ribozinoindole-1

Target: ATPase, Phosphatase

RK-9123016

T28543

Synonym: RK9123016,RK 9123016

Target: Sirtuin

Lucifer Yellow CH dilithium salt

Target: Apoptosis, Phosphatase, PERK, Autophagy, HSV

Leptomycin B

T15735

Synonym: CI 940,LMB

Target: CRM1, Antibiotic, Antifungal

CDK2 acetate(255064-79-0 free base)

Synonym: 3-Phosphohistidine

Synonym: LAI 1,Legionella autoinducer-1,Legionella autoinducer 1

Target:

Histone H3 (1-35)

T38766

Synonym: Histone H3 (1-35)

Target:

ELX-02 disulfate

T19306

Synonym: NB-124 disulfate

Synonym: (+)-Hypusine dihydrochloride,Hypusine dihydrochloride

Target:

Cefatrizine

T26973

Synonym: Cephatriazine,BL-S-640,BLS640,S 640P,BL S 640

Synonym: NB-124 sulfate

Target: Antibacterial

Didesmethylrocaglamide

Synonym: NB-124,NB 124,NB124,ELX02,ELX 02

Target:

DiZPK Hydrochloride (1337883-32-5 free base)

T15136L

Synonym: DiZPK Hydrochloride

Target: Others

カタログ番号	製品名	別名	ターゲット
TQ0131	Rocaglamide	Rocaglamide A,Roc-A	HSP , NF-κB , PERK
	Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.		HSP , NF-κB , PERK
T6512	G-418 disulfate	Geneticin,G418 Sulfate,Antibiotic G-418 sulfate,Geneticin sulfate	Antibacterial , Antibiotic
	G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic, an inhibitor of protein synthesis with eukaryotic selectivity. G-418 disulfate blocks peptide synthesis by inhibiting peptide chain elongation.		Antibacterial , Antibiotic
T7450	1-Phenylpropane-1,2-dione	1-Phenyl-1,2-propanedione,Acetyl benzoyl	Others
	1-Phenylpropane-1,2-dione (Acetyl benzoyl) is a eukaryotic metabolite produced in plant metabolic reactions.		Others
T3093	Spermine tetrahydrochloride	Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride	Others , Endogenous Metabolite
	Spermine tetrahydrochloride (Musculamine tetrahydrochloride) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free ...		Others , Endogenous Metabolite
T19083	1-Methylinosine	N1-Methylinosine,Inosine, 1-methyl	Nucleoside Antimetabolite/Analog , Endogenous Metabolite
	1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.		Nucleoside Antimetabolite/Analog , Endogenous Metabolite
T9715	Aplidine		SARS-CoV , DNA/RNA Synthesis
	Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).		SARS-CoV , DNA/RNA Synthesis
T5055	For-Met-OH	fMet,N-Formyl-L-methionine	Others , Endogenous Metabolite
	For-Met-OH (N-Formyl-L-methionine) is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formyl methionyl tRNA. This process occurs in Escherichia coli and other ...		Others , Endogenous Metabolite
T0950	Neomycin sulfate	Framycin sulfate	Phospholipase , ribosome , Antibacterial , Antibiotic
	Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prok...		Phospholipase , ribosome , Antibacterial , Antibiotic
T64911	Blasticidin S HCl		Antibiotic
	Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide...		Antibiotic
T3S1729	Dihydrolycorine		Others
	1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inh...		Others
T1022	Hygromycin B	Hygrovetine	ribosome , Antibacterial , Antibiotic , Antifungal
	Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic ...		ribosome , Antibacterial , Antibiotic , Antifungal
T73602	Phosphorylcholine	Phosphocholine	Endogenous Metabolite
	Phosphorylcholine is widely present in the biological world, which is a phospholipid present in the eukaryotic biofilm, and also in the symbiotic bacteria or pathogens associated with eukaryotes. Phosphorylcholine has im...		Endogenous Metabolite
T7961	N4-Benzoyl-2′-deoxycytidine		Others
	N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, b...		Others
T5270	5-Methylcytosine		Others , DNA/RNA Synthesis , Endogenous Metabolite
	5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...		Others , DNA/RNA Synthesis , Endogenous Metabolite
T5075	Phytic acid potassium	Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt	Others , Endogenous Metabolite
	Phytic acid potassium (Inositol polyphosphate dipotassium salt) exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3 storage depot and precursor for other inositol phosphates and pyrophosphates....		Others , Endogenous Metabolite
T2924	Phloretin	Dihydronaringenin,NSC 407292,RJC 02792	SGLT , transporter , Endogenous Metabolite
	Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav...		SGLT , transporter , Endogenous Metabolite
T2830	Betulinic acid	ALS-357,Lupatic acid,Betulic acid	Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy
	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert...
T12298	Oligomycin B		Others
	Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.		Others
T16884	Silvestrol	(-)-Silvestrol	Others
	Silvestrol is a eukaryotic translation initiation factor 4A inhibitor. Silvestrol causes autophagy and caspase-mediated apoptosis.		Others
T15094	Dehydroaltenusin		DNA/RNA Synthesis
	Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM). Dehydroaltenusin inhibits mammalian pol α activity.		DNA/RNA Synthesis
T15703	Lactimidomycin		Others
	Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferati...		Others
TN4623	Nagilactone C		Antifection
	Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C...		Antifection
TN2977	3-O-trans-p-Coumaroyltormentic acid		Caspase , Antifection
	3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, ...		Caspase , Antifection

天然物製品

Rocaglamide

TQ0131

Synonym: Rocaglamide A,Roc-A

Target: HSP, NF-κB, PERK

G-418 disulfate

T6512

Synonym: Geneticin,G418 Sulfate,Antibiotic G-418 sulfate,Geneticin sulfate

Target: Antibacterial, Antibiotic

1-Phenylpropane-1,2-dione

T7450

Synonym: 1-Phenyl-1,2-propanedione,Acetyl benzoyl

Target: Others

Spermine tetrahydrochloride

T3093

Synonym: Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride

Target: Others, Endogenous Metabolite

1-Methylinosine

T19083

Synonym: N1-Methylinosine,Inosine, 1-methyl

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Aplidine

T9715

Synonym:

Target: SARS-CoV, DNA/RNA Synthesis

For-Met-OH

T5055

Synonym: fMet,N-Formyl-L-methionine

Target: Others, Endogenous Metabolite

Neomycin sulfate

T0950

Synonym: Framycin sulfate

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Target: ribosome, Antibacterial, Antibiotic, Antifungal

Phosphorylcholine

T73602

Synonym: Phosphocholine

Target: Endogenous Metabolite

N4-Benzoyl-2′-deoxycytidine

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Phytic acid potassium

T5075

Synonym: Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt

Target: Others, Endogenous Metabolite

Phloretin

T2924

Synonym: Dihydronaringenin,NSC 407292,RJC 02792

Target: SGLT, transporter, Endogenous Metabolite

Betulinic acid

T2830

Synonym: ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

Synonym: (-)-Silvestrol

Target: DNA/RNA Synthesis

3-O-trans-p-Coumaroyltormentic acid

TN2977

Synonym:

Target: Caspase, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03608	EEF1B2 Protein, Human, Recombinant (His)	Human	E. coli
	EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, the...
TMPY-03795	EIF5A2 Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i...
TMPY-04108	EIF5A Protein, Human, Recombinant (His)	Human	E. coli
	EIF5A Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.9 kDa and the accession number is P63241-1.
TMPY-03976	EEF1E1 Protein, Human, Recombinant (His)	Human	E. coli
	EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex...
TMPY-03184	EIF5 Protein, Human, Recombinant (GST)	Human	E. coli
	EIF5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 44.1 kDa and the accession number is P55010.
TMPJ-00973	EIF1AX Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S...
TMPJ-00689	EIF1B Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 1B (EIF1B) is an element of a complex involved in recognition of the initiator codon during the scanning process. Translation is also initiated by the function of EIF1B in regulat...
TMPH-01306	EIF4A1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary str...
TMPH-01311	EIF3M Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	EIF3M Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 58.4 kDa and the accession number is Q7L2H7.
TMPJ-01109	EIF4EBP2 Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 4E-Binding Protein 2 (EIF4EBP2) is a member of the Eukaryotic Translation Initiation Factor 4E Binding Protein Family. EIF4EBP2 regulates eIF4E activity by preventing its assembly...
TMPH-03289	EIF3I Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-03288	EIF3I Protein, Rat, Recombinant (His)	Rat	Baculovirus Insect Cells
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates ...
TMPH-01309	EIF3F Protein, Human, Recombinant (His)	Human	E. coli
	EIF3F Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.5 kDa and the accession number is O00303.
TMPY-01769	4EBP1 Protein, Human, Recombinant (His)	Human	E. coli
	The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcrip...
TMPH-01307	EIF4A2 Protein, Human, Recombinant (GST)	Human	E. coli
	EIF4A2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 73.4 kDa and the accession number is Q14240.
TMPJ-00507	EIF4E Protein, Human, Recombinant	Human	E. coli
	Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and int...
TMPH-01313	EIF4G1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01312	EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)	Human	E. coli
	Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. As a member of the eIF4F c...
TMPH-01310	EIF3G Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	EIF3G Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.5 kDa and the accession number is O75821.
TMPY-03343	EIF3K Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	EIF3K is a member of the eIF3 subunit K family. It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-...
TMPY-02580	Histone H1 Protein, Human, Recombinant (His)	Human	E. coli
	H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "...
TMPH-03055	Ribonuclease mitogillin Protein, Neosartorya fumigata, Recombinant (His & Myc & SUMO)	Neosartorya fumigata	E. coli
	This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity.
TMPH-00006	Actin-1 Protein, Absidia glauca, Recombinant (His & Myc)	Absidia glauca	E. coli
	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
TMPH-03645	Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His)	Trichosanthes kirilowii	E. coli
	Inactivates eukaryotic 60S ribosomal subunits. Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 30.8 kDa and the...
TMPH-01970	EEF2KMT Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'. EEF2KMT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is ...
TMPH-00802	VacA Protein, Helicobacter pylori, Recombinant (His & SUMO)	Helicobacter pylori	E. coli
	Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions. vacA Protein, Helicobacter pylori, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted m...
TMPH-00881	ACTA1 Protein, Human, Recombinant (His)	Human	E. coli
	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA1 Protein, Human, Recombinant (His) is expressed in E. coli expression ...
TMPH-00882	ACTA2 Protein, Human, Recombinant (His)	Human	E. coli
	Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 Protein, Human, Recombinant (His) is expressed in E. coli expression ...
TMPH-00131	Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc)	Aspergillus restrictus	E. coli
	This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc) is exp...
TMPK-01516	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPH-03522	Alpha-hemolysin Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPH-03523	Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probabl...
TMPJ-00823	UBB Protein, Human, Recombinant	Human	E. coli
	Polyubiquitin-B(UBB) is one of Ubiquitins. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnorm...
TMPK-01480	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPK-01517	HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPH-03168	Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)	Pseudomonas aeruginosa	E. coli
	An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65...
TMPJ-00540	PEPD Protein, Human, Recombinant	Human	E. coli
	PEPD belongs to the peptidase M24B family of Eukaryotic-type prolidase subfamily. PEPD is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus. It is important in coll...
TMPH-00206	Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO)	Bordetella pertussis	E. coli
	Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping c...
TMPJ-01202	LYG2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lysozyme G-Like Protein 2 (LYG2) is a secreted protein that belongs to the glycosyl hydrolase 23 family. LYG2 contains one SLT domain, one protein domain present in bacterial lytic transglycosylase (SLT) and in eukaryoti...
TMPH-00106	TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)	Arabidopsis thaliana	E. coli
	General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a ro...
TMPH-00120	Ribonuclease clavin Protein, Aspergillus clavatus, Recombinant (His & Myc)	Aspergillus clavatus	E. coli
	Clavin has the same substrate specificity as alpha-sarcin. It is specific for purines in both single- and double-stranded RNA. Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bon...
TMPY-02002	PHPT1 Protein, Human, Recombinant (His)	Human	E. coli
	PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in...
TMPY-04402	CSNK1G1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are ...
TMPH-01800	Nucleolin Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is ...
TMPH-00419	Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc)	C.perfringens	E. coli
	Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization. Has both...
TMPJ-01257	PMM1 Protein, Human, Recombinant (His)	Human	E. coli
	Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. G...
TMPJ-01395	NIP7 Protein, Human, Recombinant (His)	Human	E. coli
	60S Ribosome Subunit Biogenesis Protein NIP7 Homolog (NIP7) belongs to the NIP7 family. NIP7 contains one PUA domain, it is essential for the process of proper 27S pre-rRNA and 60S ribosome subunit assembly. NIP7 is a mo...
TMPY-03990	Profilin 4 Protein, Human, Recombinant (His)	Human	E. coli
	PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilamen...
TMPJ-00918	HMGB2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cell...
TMPJ-00508	CTSL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tu...
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EEF1B2 Protein, Human, Recombinant (His)

TMPY-03608

Species: Human

Expression System: E. coli

EIF5A2 Protein, Human, Recombinant (His)

TMPY-03795

Species: Human

Expression System: E. coli

EIF5A Protein, Human, Recombinant (His)

TMPY-04108

Species: Human

Expression System: E. coli

EEF1E1 Protein, Human, Recombinant (His)

TMPY-03976

Species: Human

Expression System: E. coli

EIF5 Protein, Human, Recombinant (GST)

TMPY-03184

Species: Human

Expression System: E. coli

EIF1AX Protein, Human, Recombinant (His)

TMPJ-00973

Species: Human

Expression System: E. coli

EIF1B Protein, Human, Recombinant (His)

TMPJ-00689

Species: Human

Expression System: E. coli

EIF4A1 Protein, Human, Recombinant (His & Myc)

TMPH-01306

Species: Human

Expression System: E. coli

EIF3M Protein, Human, Recombinant (His & SUMO)

TMPH-01311

Species: Human

Expression System: E. coli

EIF4EBP2 Protein, Human, Recombinant (His)

TMPJ-01109

Species: Human

Expression System: E. coli

EIF3I Protein, Rat, Recombinant (E. coli, His)

TMPH-03289

Species: Rat

Expression System: E. coli

EIF3I Protein, Rat, Recombinant (His)

TMPH-03288

Species: Rat

Expression System: Baculovirus Insect Cells

EIF3F Protein, Human, Recombinant (His)

TMPH-01309

Species: Human

Expression System: E. coli

4EBP1 Protein, Human, Recombinant (His)

TMPY-01769

Species: Human

Expression System: E. coli

EIF4A2 Protein, Human, Recombinant (GST)

TMPH-01307

Species: Human

Expression System: E. coli

EIF4E Protein, Human, Recombinant

TMPJ-00507

Species: Human

Expression System: E. coli

EIF4G1 Protein, Human, Recombinant (His)

TMPH-01313

Species: Human

Expression System: P. pastoris (Yeast)

EIF4G1 Protein, Human, Recombinant (B2M & His & JD & Myc)

TMPH-01312

Species: Human

Expression System: E. coli

EIF3G Protein, Human, Recombinant (His & SUMO)

TMPH-01310

Species: Human

Expression System: E. coli

EIF3K Protein, Human, Recombinant (His & GST)

TMPY-03343

Species: Human

Expression System: Baculovirus Insect Cells

Histone H1 Protein, Human, Recombinant (His)

TMPY-02580

Species: Human

Expression System: E. coli

Ribonuclease mitogillin Protein, Neosartorya fumigata, Recombinant (His & Myc & SUMO)

TMPH-03055

Species: Neosartorya fumigata

Expression System: E. coli

Actin-1 Protein, Absidia glauca, Recombinant (His & Myc)

TMPH-00006

Species: Absidia glauca

Expression System: E. coli

Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His)

TMPH-03645

Species: Trichosanthes kirilowii

Expression System: E. coli

EEF2KMT Protein, Human, Recombinant (His)

TMPH-01970

Species: Human

Expression System: E. coli

vacA Protein, Helicobacter pylori, Recombinant (His & SUMO)

TMPH-00802

Species: Helicobacter pylori

Expression System: E. coli

ACTA1 Protein, Human, Recombinant (His)

TMPH-00881

Species: Human

Expression System: E. coli

ACTA2 Protein, Human, Recombinant (His)

TMPH-00882

Species: Human

Expression System: E. coli

Ribonuclease mitogillin Protein, Aspergillus restrictus, Recombinant (His & Myc)

TMPH-00131

Species: Aspergillus restrictus

Expression System: E. coli

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01516

Species: Human

Expression System: HEK293 Cells

Alpha-hemolysin Protein, S. aureus, Recombinant (His)

TMPH-03522

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03523

Species: Staphylococcus aureus

Expression System: E. coli

UBB Protein, Human, Recombinant

TMPJ-00823

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01480

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)

TMPK-01517

Species: Human

Expression System: HEK293 Cells

Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)

TMPH-03168

Species: Pseudomonas aeruginosa

Expression System: E. coli

PEPD Protein, Human, Recombinant

TMPJ-00540

Species: Human

Expression System: E. coli

Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO)

TMPH-00206

Species: Bordetella pertussis

Expression System: E. coli

LYG2 Protein, Human, Recombinant (His)

TMPJ-01202

Species: Human

Expression System: HEK293 Cells

TBP1 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)

TMPH-00106

Species: Arabidopsis thaliana

Expression System: E. coli

Ribonuclease clavin Protein, Aspergillus clavatus, Recombinant (His & Myc)

TMPH-00120

Species: Aspergillus clavatus

Expression System: E. coli

PHPT1 Protein, Human, Recombinant (His)

TMPY-02002

Species: Human

Expression System: E. coli

CSNK1G1 Protein, Human, Recombinant (His & GST)

TMPY-04402

Species: Human

Expression System: Baculovirus Insect Cells

Nucleolin Protein, Human, Recombinant (His)

TMPH-01800

Species: Human

Expression System: P. pastoris (Yeast)

Microbial collagenase Protein, Clostridium perfringens, Recombinant (His & Myc)

TMPH-00419

Species: C.perfringens

Expression System: E. coli

PMM1 Protein, Human, Recombinant (His)

TMPJ-01257

Species: Human

Expression System: E. coli

NIP7 Protein, Human, Recombinant (His)

TMPJ-01395

Species: Human

Expression System: E. coli

Profilin 4 Protein, Human, Recombinant (His)

TMPY-03990

Species: Human

Expression System: E. coli

HMGB2 Protein, Human, Recombinant (His)

TMPJ-00918

Species: Human

Expression System: HEK293 Cells

CTSL Protein, Human, Recombinant (His)

TMPJ-00508

Species: Human

Expression System: HEK293 Cells

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カタログ番号	製品名
L1110	Microtubule-Targeted Compound Library	142 compounds
	A unique collection of 142 microtubule-targeted compounds can be used in HTS and HCS;
L1310	Cytoskeletal Signaling Pathway Compound Library	759 compounds
	A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS；
L5300	Mitochondria-Targeted Compound Library	812 compounds
	A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;

ライブラリー

Microtubule-Targeted Compound Library

L1110

Compounds: 142

Cytoskeletal Signaling Pathway Compound Library

L1310

Compounds: 759

Mitochondria-Targeted Compound Library

L5300

Compounds: 812