Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) in humans and rats. GW274150 showed protective effects in an inflammatory model of acute lung injury.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 27,000 | |||
5 mg | 在庫あり | ¥ 64,000 | |||
10 mg | 在庫あり | ¥ 94,000 | |||
25 mg | 在庫あり | ¥ 151,000 | |||
50 mg | 在庫あり | ¥ 206,500 | |||
100 mg | 在庫あり | ¥ 310,000 | |||
500 mg | 在庫あり | お問い合わせ |
ターゲット&IC50 | nNOS (rat):252 μM(ED50), iNOS (human):2.19 μM(kd), eNOS (human):544 μM(kd), iNOS:(kd)40 nM, iNOS (rat): 1.15 μM(ED50), nNOS (human):177 μM(kd), iNOS:40 nM(kd), iNOS (rat):1.15 μM(ED50) |
分子量 | 219.3 |
分子式 | C8H17N3O2S |
CAS No. | 210354-22-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: < 1 mg/mL (insoluble or slightly soluble)
H2O: 50 mg/mL (228 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GW274150 210354-22-6 Immunology/Inflammation NOS GW 274150 GW-274150 Inhibitor inhibitor inhibit