Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 7,000 | |||
5 mg | 在庫あり | ¥ 14,000 | |||
10 mg | 在庫あり | ¥ 27,000 | |||
25 mg | 在庫あり | ¥ 48,500 | |||
50 mg | 在庫あり | ¥ 66,500 | |||
100 mg | 在庫あり | ¥ 98,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 15,500 |
説明 | Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen. |
In vivo | Guggulsterone E&Z inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP, and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases, inhibition of Akt, and activation of JNK.?Guggulsterone E&Z modulates the expression of gene products involved in metastasis (MMP-9, COX-2, and VEGF) of tumor cells. |
植物由来 |
別名 | Guggulsterone E&Z |
分子量 | 312.45 |
分子式 | C21H28O2 |
CAS No. | 95975-55-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20.83 mg/mL (66.67 mM)
You can also refer to dose conversion for different animals. 詳細
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Guggulsterone 95975-55-6 Apoptosis Autophagy Cytoskeletal Signaling MAPK Metabolism PI3K/Akt/mTOR signaling Proteases/Proteasome Akt Caspase JNK FXR Z/E-Guggulsterone Inhibitor inhibit Protein kinase B Guggulsterone E&Z PKB NR1H4 inhibitor