Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
説明 | Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration. |
In vitro | Imeglimin dramatically decreased reactive oxygen species production, inhibiting specifically reverse electron transfer through complex I. Imeglimin prevents hyperglycemia-induced cell death in HMEC-1 through inhibition of PTP opening without inhibiting mitochondrial respiration nor affecting cellular energy status[1]. |
別名 | EMD 387008 hydrochloride |
分子量 | 191.66 |
分子式 | C6H14ClN5 |
CAS No. | 775351-61-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (286.97 mM)
You can also refer to dose conversion for different animals. 詳細
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Imeglimin hydrochloride 775351-61-6 Immunology/Inflammation Metabolism NF-Κb Mitochondrial Metabolism Reactive Oxygen Species EMD387008 EMD 387008 hydrochloride inhibit mitochondrial lowering insulin oral Imeglimin Hydrochloride ROS Imeglimin Inhibitor function EMD-387008 EMD387008 Hydrochloride sensitivity EMD 387008 EMD 387008 Hydrochloride EMD-387008 Hydrochloride glucose inhibitor